U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

THBS3 thrombospondin 3 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 717572, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
THBS3provided by VGNC
Official Full Name
thrombospondin 3provided by VGNC
Primary source
VGNC:VGNC:78345
Locus tag
EGK_01383
See related
Ensembl:ENSMMUG00000003902
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See THBS3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
24
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (95820736..95834926)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (129892273..129906834, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene metaxin-1-like Neighboring gene lysosomal acid glucosylceramidase-like Neighboring gene metaxin-1 Neighboring gene uncharacterized LOC114670471 Neighboring gene microRNA mir-92b Neighboring gene mucin 1, cell surface associated

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
thrombospondin-3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001260514.1 → NP_001247443.1  thrombospondin-3 precursor

    See identical proteins and their annotated locations for NP_001247443.1

    Status: PROVISIONAL

    Source sequence(s)
    JV048084
    UniProtKB/TrEMBL
    A0A8J8Y2S0, F6TTV4, F6ZVD5, I0FUM9
    Related
    ENSMMUP00000038872.3, ENSMMUT00000045827.3
    Conserved Domains (9) summary
    smart00210
    Location:23 → 193
    TSPN; Thrombospondin N-terminal -like domains
    cd00054
    Location:316 → 351
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:528 → 550
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:551 → 586
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:458 → 491
    TSP3_1C; TSP3 repeat_1C [structural motif]
    pfam02412
    Location:552 → 586
    TSP_3; Thrombospondin type 3 repeat
    pfam05735
    Location:741 → 938
    TSP_C; Thrombospondin C-terminal region
    pfam12947
    Location:378 → 407
    EGF_3; EGF domain
    cd16079
    Location:227 → 269
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    95820736..95834926
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028845885.1 → XP_028701718.1  thrombospondin-3 isoform X4

    UniProtKB/TrEMBL
    A0A1D5RD40, F6TTV4
    Related
    ENSMMUP00000058233.2, ENSMMUT00000071203.2
    Conserved Domains (10) summary
    cd00054
    Location:278 → 313
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:490 → 512
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:513 → 548
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:420 → 453
    TSP3_1C; TSP3 repeat_1C [structural motif]
    cd16079
    Location:189 → 231
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    pfam02412
    Location:513 → 548
    TSP_3; Thrombospondin type 3 repeat
    pfam12947
    Location:340 → 369
    EGF_3; EGF domain
    NF000535
    Location:411 → 614
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    pfam05735
    Location:703 → 900
    TSP_C; Thrombospondin C-terminal region
    cl22861
    Location:2 → 155
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

  2. XM_015109964.2 → XP_014965450.2  thrombospondin-3 isoform X1

    UniProtKB/TrEMBL
    F6TTV4
    Conserved Domains (10) summary
    cd00054
    Location:342 → 377
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:554 → 576
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:577 → 612
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:484 → 517
    TSP3_1C; TSP3 repeat_1C [structural motif]
    cd16079
    Location:253 → 295
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    pfam02412
    Location:577 → 612
    TSP_3; Thrombospondin type 3 repeat
    pfam12947
    Location:404 → 433
    EGF_3; EGF domain
    NF000535
    Location:475 → 678
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    pfam05735
    Location:767 → 964
    TSP_C; Thrombospondin C-terminal region
    cl22861
    Location:52 → 219
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

  3. XM_028845875.1 → XP_028701708.1  thrombospondin-3 isoform X2

    UniProtKB/TrEMBL
    A0A1D5Q586
    Conserved Domains (10) summary
    cd00054
    Location:333 → 368
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:545 → 567
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:568 → 603
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:475 → 508
    TSP3_1C; TSP3 repeat_1C [structural motif]
    cd16079
    Location:244 → 286
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    pfam02412
    Location:568 → 603
    TSP_3; Thrombospondin type 3 repeat
    pfam12947
    Location:395 → 424
    EGF_3; EGF domain
    NF000535
    Location:466 → 669
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    pfam05735
    Location:758 → 955
    TSP_C; Thrombospondin C-terminal region
    cl22861
    Location:52 → 219
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

  4. XM_028845881.1 → XP_028701714.1  thrombospondin-3 isoform X3

    UniProtKB/TrEMBL
    F6TTV4
    Related
    ENSMMUP00000043201.2, ENSMMUT00000073102.2
    Conserved Domains (10) summary
    smart00210
    Location:23 → 193
    TSPN; Thrombospondin N-terminal -like domains
    cd00054
    Location:307 → 342
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:519 → 541
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:542 → 577
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:449 → 482
    TSP3_1C; TSP3 repeat_1C [structural motif]
    cd16079
    Location:218 → 260
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    pfam02412
    Location:542 → 577
    TSP_3; Thrombospondin type 3 repeat
    pfam12947
    Location:369 → 398
    EGF_3; EGF domain
    NF000535
    Location:440 → 643
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    pfam05735
    Location:732 → 929
    TSP_C; Thrombospondin C-terminal region

  5. XM_015109983.2 → XP_014965469.2  thrombospondin-3 isoform X5

    Conserved Domains (9) summary
    cd00054
    Location:61 → 96
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:273 → 295
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:296 → 331
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:203 → 236
    TSP3_1C; TSP3 repeat_1C [structural motif]
    cl13107
    Location:1 → 14
    TSPcc; Coiled coil region of thrombospondin
    pfam02412
    Location:296 → 331
    TSP_3; Thrombospondin type 3 repeat
    pfam12947
    Location:123 → 152
    EGF_3; EGF domain
    NF000535
    Location:194 → 421
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    pfam05735
    Location:486 → 683
    TSP_C; Thrombospondin C-terminal region

  6. XM_015109987.2 → XP_014965473.2  thrombospondin-3 isoform X6

    Conserved Domains (8) summary
    cd00054
    Location:27 → 62
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:239 → 261
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:262 → 297
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:169 → 202
    TSP3_1C; TSP3 repeat_1C [structural motif]
    pfam02412
    Location:262 → 297
    TSP_3; Thrombospondin type 3 repeat
    pfam12947
    Location:89 → 118
    EGF_3; EGF domain
    NF000535
    Location:160 → 387
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    pfam05735
    Location:452 → 649
    TSP_C; Thrombospondin C-terminal region

RNA

  1. XR_003728175.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.