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CD44 CD44 molecule [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 717204, updated on 17-Aug-2024

Summary

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Official Symbol
CD44provided by VGNC
Official Full Name
CD44 moleculeprovided by VGNC
Primary source
VGNC:VGNC:100905
Locus tag
EGK_06355
See related
Ensembl:ENSMMUG00000004327
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See CD44 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
18
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (30238717..30330444, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (30685527..30777522, complement)

Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene peptidase domain containing associated with muscle regeneration 1 Neighboring gene solute carrier family 1 member 2 Neighboring gene uncharacterized LOC106993295 Neighboring gene uncharacterized LOC106993296

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of macrophage migration inhibitory factor receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CD44 antigen
Names
CD44 molecule (Indian blood group)
Phagocytic glycoprotein I

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041767.1 Reference Mmul_10 Primary Assembly

    Range
    30238717..30330444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015114531.2 → XP_014970017.1  CD44 antigen isoform X6

    UniProtKB/TrEMBL
    F6ZDW3
    Conserved Domains (2) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
    pfam11725
    Location:335 → 487
    AvrE; Pathogenicity factor

  2. XM_015114527.2 → XP_014970013.1  CD44 antigen isoform X2

    UniProtKB/TrEMBL
    A0A663DBE7, A0A8J8XS81, F6ZDW3, F6ZDZ8, G7NDL1
    Related
    ENSMMUP00000005783.3, ENSMMUT00000006142.4
    Conserved Domains (2) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
    pfam11725
    Location:378 → 530
    AvrE; Pathogenicity factor

  3. XM_015114538.2 → XP_014970024.1  CD44 antigen isoform X16

    UniProtKB/TrEMBL
    F6ZDX2, H9Z063
    Related
    ENSMMUP00000080953.1, ENSMMUT00000093498.1
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  4. XM_028833521.1 → XP_028689354.1  CD44 antigen isoform X15

    UniProtKB/TrEMBL
    A0A5F8AL78, F6ZDX2
    Related
    ENSMMUP00000078153.1, ENSMMUT00000092665.1
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  5. XM_001115390.4 → XP_001115390.1  CD44 antigen isoform X13

    See identical proteins and their annotated locations for XP_001115390.1

    UniProtKB/TrEMBL
    A0A5F8A6T9
    Related
    ENSMMUP00000073570.1, ENSMMUT00000102090.1
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  6. XM_028833520.1 → XP_028689353.1  CD44 antigen isoform X14

    UniProtKB/TrEMBL
    A0A5F8A6T9, F6ZDY1
    Related
    ENSMMUP00000005785.4, ENSMMUT00000006144.4
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  7. XM_015114537.2 → XP_014970023.1  CD44 antigen isoform X12

    UniProtKB/TrEMBL
    A0A5F8A6T9
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  8. XM_015114536.2 → XP_014970022.1  CD44 antigen isoform X11

    UniProtKB/TrEMBL
    A0A1D5QRB0, A0A5F8A6T9
    Related
    ENSMMUP00000050588.2, ENSMMUT00000058333.2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  9. XM_015114535.2 → XP_014970021.1  CD44 antigen isoform X10

    UniProtKB/TrEMBL
    F6ZDW3
    Conserved Domains (2) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
    pfam11725
    Location:293 → 445
    AvrE; Pathogenicity factor

  10. XM_015114534.2 → XP_014970020.1  CD44 antigen isoform X9

    UniProtKB/TrEMBL
    F6ZDW3
    Conserved Domains (2) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
    pfam11725
    Location:294 → 446
    AvrE; Pathogenicity factor

  11. XM_015114530.2 → XP_014970016.1  CD44 antigen isoform X5

    UniProtKB/TrEMBL
    F6ZDW3
    Conserved Domains (2) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
    pfam11725
    Location:336 → 488
    AvrE; Pathogenicity factor

  12. XM_015114532.2 → XP_014970018.1  CD44 antigen isoform X8

    UniProtKB/TrEMBL
    F6ZDW3
    Related
    ENSMMUP00000005787.4, ENSMMUT00000006146.4
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  13. XM_015114533.2 → XP_014970019.1  CD44 antigen isoform X7

    UniProtKB/TrEMBL
    F6ZDW3
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  14. XM_015114529.2 → XP_014970015.1  CD44 antigen isoform X4

    UniProtKB/TrEMBL
    F6ZDW3
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  15. XM_015114528.2 → XP_014970014.1  CD44 antigen isoform X3

    UniProtKB/TrEMBL
    F6ZDW3
    Conserved Domains (2) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
    pfam11725
    Location:379 → 530
    AvrE; Pathogenicity factor

  16. XM_001115359.4 → XP_001115359.2  CD44 antigen isoform X1

    UniProtKB/TrEMBL
    F6ZDW3
    Conserved Domains (2) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
    pfam11725
    Location:379 → 531
    AvrE; Pathogenicity factor
Nucleotide Protein
Heading Accession and Version

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