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TLK2 tousled like kinase 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716528, updated on 17-Aug-2024

Summary

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Official Symbol
TLK2provided by VGNC
Official Full Name
tousled like kinase 2provided by VGNC
Primary source
VGNC:VGNC:78368
See related
Ensembl:ENSMMUG00000002166
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See TLK2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (58915535..59057957)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (56082315..56226711)

Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene EF-hand calcium-binding domain-containing protein 3 Neighboring gene 40S ribosomal protein S23-like Neighboring gene methyltransferase 2A, tRNA N3-cytidine Neighboring gene U6 spliceosomal RNA Neighboring gene mannose receptor C-type 2 Neighboring gene membrane associated ring-CH-type finger 10 Neighboring gene uncharacterized LOC100428387

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromosome segregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase tousled-like 2
XP_014975518.1
XP_014975519.1
XP_014975520.1
XP_014975521.1
XP_014975522.1
XP_028692462.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041769.1 Reference Mmul_10 Primary Assembly

    Range
    58915535..59057957
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015120032.2 → XP_014975518.1  serine/threonine-protein kinase tousled-like 2 isoform X1

    UniProtKB/TrEMBL
    A0A1D5RCE0, H9EN28
    Conserved Domains (2) summary
    COG1196
    Location:206 → 503
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd14041
    Location:433 → 741
    STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2

  2. XM_015120034.2 → XP_014975520.1  serine/threonine-protein kinase tousled-like 2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5RCE0, F7G1N1, H9EN29
    Related
    ENSMMUP00000014069.4, ENSMMUT00000015015.4
    Conserved Domains (2) summary
    COG1196
    Location:174 → 471
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd14041
    Location:401 → 709
    STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2

  3. XM_015120033.2 → XP_014975519.1  serine/threonine-protein kinase tousled-like 2 isoform X1

    UniProtKB/TrEMBL
    A0A1D5RCE0, H9EN28
    Related
    ENSMMUP00000057982.2, ENSMMUT00000067095.2
    Conserved Domains (2) summary
    COG1196
    Location:206 → 503
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd14041
    Location:433 → 741
    STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2

  4. XM_015120035.2 → XP_014975521.1  serine/threonine-protein kinase tousled-like 2 isoform X3

    UniProtKB/TrEMBL
    A0A1D5RCE0
    Conserved Domains (2) summary
    COG1196
    Location:102 → 399
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd14041
    Location:329 → 637
    STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2

  5. XM_015120036.2 → XP_014975522.1  serine/threonine-protein kinase tousled-like 2 isoform X3

    UniProtKB/TrEMBL
    A0A1D5RCE0
    Conserved Domains (2) summary
    COG1196
    Location:102 → 399
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd14041
    Location:329 → 637
    STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2

  6. XM_028836629.1 → XP_028692462.1  serine/threonine-protein kinase tousled-like 2 isoform X4

    UniProtKB/TrEMBL
    A0A1D5RCE0
    Conserved Domains (2) summary
    COG1196
    Location:57 → 354
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd14041
    Location:284 → 592
    STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2
Nucleotide Protein
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