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GZMB granzyme B [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716518, updated on 17-Aug-2024

Summary

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Official Symbol
GZMBprovided by VGNC
Official Full Name
granzyme Bprovided by VGNC
Primary source
VGNC:VGNC:73337
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See GZMB in Genome Data Viewer
Location:
chromosome: 7
Exon count:
5
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (86703929..86707259, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (86027765..86031101, complement)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene cathepsin G Neighboring gene granzyme H Neighboring gene U6 spliceosomal RNA Neighboring gene syntaxin binding protein 6 Neighboring gene uncharacterized LOC114679542

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
granzyme B
Names
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    86703929..86707259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001114420.4 → XP_001114420.3  granzyme B

    UniProtKB/TrEMBL
    G7MXD7
    Conserved Domains (1) summary
    cd00190
    Location:55 → 277
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version

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