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SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716067, updated on 17-Aug-2024

Summary

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Official Symbol
SMARCA4provided by VGNC
Official Full Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4provided by VGNC
Primary source
VGNC:VGNC:77648
Locus tag
EGK_10116
See related
Ensembl:ENSMMUG00000012042
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SMARCA4 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
37
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (10726550..10829142)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (11003771..11082506)

Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene coactivator associated arginine methyltransferase 1 Neighboring gene Yip1 domain family member 2 Neighboring gene translocase of inner mitochondrial membrane 29 Neighboring gene low density lipoprotein receptor Neighboring gene uncharacterized LOC114674158 Neighboring gene SPC24 component of NDC80 kinetochore complex

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription activator BRG1
Names
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4
transcription activator BRG1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041772.1 Reference Mmul_10 Primary Assembly

    Range
    10726550..10829142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028839586.1 → XP_028695419.1  transcription activator BRG1 isoform X1

    UniProtKB/TrEMBL
    H9ZCL5
    Conserved Domains (9) summary
    cd05516
    Location:1493 → 1599
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612 → 656
    BRK; domain in transcription and CHROMO domain helicases
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1322 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4

  2. XM_028839587.1 → XP_028695420.1  transcription activator BRG1 isoform X1

    UniProtKB/TrEMBL
    H9ZCL5
    Conserved Domains (9) summary
    cd05516
    Location:1493 → 1599
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612 → 656
    BRK; domain in transcription and CHROMO domain helicases
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1322 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4

  3. XM_028839590.1 → XP_028695423.1  transcription activator BRG1 isoform X3

    UniProtKB/TrEMBL
    A0A5S6RCM2, A0A8J8Y4Y4, F7GWD7, G7NL17, H9ZCL5
    Related
    ENSMMUP00000015797.4, ENSMMUT00000016867.4
    Conserved Domains (9) summary
    cd05516
    Location:1490 → 1596
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07533
    Location:612 → 654
    BRK; BRK domain
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1323 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

  4. XM_028839594.1 → XP_028695427.1  transcription activator BRG1 isoform X6

    UniProtKB/TrEMBL
    H9ZCL5
    Conserved Domains (9) summary
    cd05516
    Location:1458 → 1564
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07533
    Location:612 → 654
    BRK; BRK domain
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1323 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

  5. XM_028839585.1 → XP_028695418.1  transcription activator BRG1 isoform X1

    UniProtKB/TrEMBL
    H9ZCL5
    Conserved Domains (9) summary
    cd05516
    Location:1493 → 1599
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612 → 656
    BRK; domain in transcription and CHROMO domain helicases
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1322 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4

  6. XM_028839588.1 → XP_028695421.1  transcription activator BRG1 isoform X2

    UniProtKB/TrEMBL
    H9ZCL5
    Conserved Domains (9) summary
    cd05516
    Location:1493 → 1598
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612 → 656
    BRK; domain in transcription and CHROMO domain helicases
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1322 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4

  7. XM_028839589.1 → XP_028695422.1  transcription activator BRG1 isoform X3

    UniProtKB/TrEMBL
    A0A5S6RCM2, A0A8J8Y4Y4, F7GWD7, G7NL17, H9ZCL5
    Conserved Domains (9) summary
    cd05516
    Location:1490 → 1596
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07533
    Location:612 → 654
    BRK; BRK domain
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1323 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

  8. XM_028839591.1 → XP_028695424.1  transcription activator BRG1 isoform X4

    UniProtKB/TrEMBL
    H9ZCL5
    Conserved Domains (9) summary
    cd05516
    Location:1461 → 1567
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07533
    Location:612 → 654
    BRK; BRK domain
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1323 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

  9. XM_028839593.1 → XP_028695426.1  transcription activator BRG1 isoform X6

    UniProtKB/TrEMBL
    H9ZCL5
    Conserved Domains (9) summary
    cd05516
    Location:1458 → 1564
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07533
    Location:612 → 654
    BRK; BRK domain
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1323 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

  10. XM_028839596.1 → XP_028695429.1  transcription activator BRG1 isoform X8

    UniProtKB/TrEMBL
    H9ZCL5
    Conserved Domains (9) summary
    cd05516
    Location:1458 → 1563
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07533
    Location:612 → 654
    BRK; BRK domain
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1323 → 1389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

  11. XM_028839592.1 → XP_028695425.1  transcription activator BRG1 isoform X5

    UniProtKB/TrEMBL
    H9ZCL7
    Conserved Domains (9) summary
    cd05516
    Location:1460 → 1566
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612 → 656
    BRK; domain in transcription and CHROMO domain helicases
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1289 → 1356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4

  12. XM_028839595.1 → XP_028695428.1  transcription activator BRG1 isoform X7

    UniProtKB/TrEMBL
    A0A1D5RBB4, H9FYR1, H9ZCL8
    Related
    ENSMMUP00000057605.2, ENSMMUT00000075604.2
    Conserved Domains (9) summary
    cd05516
    Location:1457 → 1563
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07533
    Location:612 → 654
    BRK; BRK domain
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1290 → 1356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

  13. XM_028839597.1 → XP_028695430.1  transcription activator BRG1 isoform X9

    UniProtKB/TrEMBL
    H9FYR2, H9ZCL9
    Related
    ENSMMUP00000048927.2, ENSMMUT00000064824.2
    Conserved Domains (9) summary
    cd05516
    Location:1425 → 1531
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07533
    Location:612 → 654
    BRK; BRK domain
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1290 → 1356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

  14. XM_028839598.1 → XP_028695431.1  transcription activator BRG1 isoform X10

    UniProtKB/TrEMBL
    H9ZCL9
    Conserved Domains (9) summary
    cd05516
    Location:1425 → 1530
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612 → 656
    BRK; domain in transcription and CHROMO domain helicases
    smart00573
    Location:460 → 532
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:750 → 1232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370 → 552
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42 → 222
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731 → 981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam08880
    Location:171 → 205
    QLQ
    pfam14619
    Location:1289 → 1356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
Nucleotide Protein
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