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DPYD dihydropyrimidine dehydrogenase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 715672, updated on 17-Aug-2024

Summary

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Official Symbol
DPYDprovided by VGNC
Official Full Name
dihydropyrimidine dehydrogenaseprovided by VGNC
Primary source
VGNC:VGNC:71982
See related
Ensembl:ENSMMUG00000020726
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DPYD in Genome Data Viewer
Location:
chromosome: 1
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (126215291..127076677)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (97818320..98681591, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999831 Neighboring gene microRNA mir-137 Neighboring gene zinc finger protein 131 pseudogene Neighboring gene uncharacterized LOC114678173 Neighboring gene sorting nexin-7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables dihydropyrimidine dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables uracil binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in thymine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in uracil catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dihydropyrimidine dehydrogenase [NADP(+)]

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    126215291..127076677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015145562.2 → XP_015001048.2  dihydropyrimidine dehydrogenase [NADP(+)]

    UniProtKB/TrEMBL
    A0A5F7ZRM8, G7MI45
    Related
    ENSMMUP00000067300.1, ENSMMUT00000091392.1
    Conserved Domains (3) summary
    PRK11749
    Location:53 → 513
    PRK11749; dihydropyrimidine dehydrogenase subunit A; Provisional
    cd02940
    Location:532 → 834
    DHPD_FMN; Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and ...
    pfam14697
    Location:946 → 1004
    Fer4_21; 4Fe-4S dicluster domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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