U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fam83c family with sequence similarity 83, member C [ Mus musculus (house mouse) ]

Gene ID: 71405, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Fam83cprovided by MGI
Official Full Name
family with sequence similarity 83, member Cprovided by MGI
Primary source
MGI:MGI:1918655
See related
Ensembl:ENSMUSG00000074647 AllianceGenome:MGI:1918655
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5530400B04Rik
Summary
Predicted to enable protein kinase binding activity. Predicted to be involved in epidermal growth factor receptor signaling pathway. Orthologous to human FAM83C (family with sequence similarity 83 member C). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in stomach adult (RPKM 9.8), colon adult (RPKM 5.4) and 6 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Fam83c in Genome Data Viewer
Location:
2 H1; 2 77.26 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (155671103..155676772, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (155829183..155834852, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 24 Neighboring gene STARR-positive B cell enhancer ABC_E4512 Neighboring gene matrix metallopeptidase 24 opposite strand transcript 1 Neighboring gene eukaryotic translation initiation factor 6 Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 1 Neighboring gene predicted gene, 54125 Neighboring gene STARR-seq mESC enhancer starr_06151 Neighboring gene growth differentiation factor 5

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC133000, MGC133001

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in epidermal growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein FAM83C
Names
ortholog of family with sequence similarity 83, member C FAM83C (5530400B04Rik)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027788.3 → NP_082064.3  protein FAM83C

    Status: VALIDATED

    Source sequence(s)
    AL845445
    Consensus CDS
    CCDS50770.1
    UniProtKB/Swiss-Prot
    A2ARK0, Q14CG2
    UniProtKB/TrEMBL
    A0A6Q6PLP7
    Related
    ENSMUSP00000159338.2, ENSMUST00000239423.2
    Conserved Domains (2) summary
    PHA03247
    Location:291 → 471
    PHA03247; large tegument protein UL36; Provisional
    cl15239
    Location:20 → 289
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    155671103..155676772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2ARK0.1 GenPept UniProtKB/Swiss-Prot:A2ARK0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools