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PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 713062, updated on 17-Aug-2024

Summary

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Official Symbol
PFKFB3provided by VGNC
Official Full Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3provided by VGNC
Primary source
VGNC:VGNC:75959
See related
Ensembl:ENSMMUG00000010596
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PFKFB3 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (7326000..7416148)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (6075203..6166375)

Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000030 Neighboring gene RNA binding motif protein 17 Neighboring gene protein kinase C theta Neighboring gene uncharacterized LOC107000031

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041762.1 Reference Mmul_10 Primary Assembly

    Range
    7326000..7416148
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015146419.2 → XP_015001905.2  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1

    Conserved Domains (3) summary
    pfam12877
    Location:7 → 96
    DUF3827; Domain of unknown function (DUF3827)
    pfam00300
    Location:371 → 554
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:149 → 368
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_028825949.1 → XP_028681782.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X3

    Conserved Domains (3) summary
    pfam12877
    Location:7 → 96
    DUF3827; Domain of unknown function (DUF3827)
    pfam00300
    Location:371 → 554
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:149 → 368
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_002805545.3 → XP_002805591.2  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2

    Conserved Domains (3) summary
    pfam12877
    Location:7 → 96
    DUF3827; Domain of unknown function (DUF3827)
    pfam00300
    Location:371 → 554
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:149 → 368
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_015146420.2 → XP_015001906.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X6

    UniProtKB/TrEMBL
    G7N1J4
    Related
    ENSMMUP00000013893.4, ENSMMUT00000014828.4
    Conserved Domains (2) summary
    pfam00300
    Location:210 → 396
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 207
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_015146416.2 → XP_015001902.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X4

    UniProtKB/TrEMBL
    F7CGS8
    Related
    ENSMMUP00000013888.4, ENSMMUT00000014823.4
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 246
    6PF2K; 6-phosphofructo-2-kinase

  6. XM_001107535.4 → XP_001107535.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X5

    See identical proteins and their annotated locations for XP_001107535.1

    UniProtKB/TrEMBL
    F7CGA2, H9FVS8
    Related
    ENSMMUP00000063452.1, ENSMMUT00000099182.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 246
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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