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AIRE autoimmune regulator [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 712858, updated on 17-Aug-2024

Summary

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Official Symbol
AIREprovided by VGNC
Official Full Name
autoimmune regulatorprovided by VGNC
Primary source
VGNC:VGNC:69760
See related
Ensembl:ENSMMUG00000004168
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See AIRE in Genome Data Viewer
Location:
chromosome: 3
Exon count:
15
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (2436714..2450174, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (2428125..2441439, complement)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106997221 Neighboring gene cilia and flagella associated protein 410 Neighboring gene phosphofructokinase, liver type Neighboring gene DNA methyltransferase 3 like Neighboring gene uncharacterized LOC106997222 Neighboring gene uncharacterized LOC106997223

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in humoral immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
autoimmune regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    2436714..2450174 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028845275.1 → XP_028701108.1  autoimmune regulator isoform X1

    UniProtKB/TrEMBL
    G7MMH4
    Conserved Domains (4) summary
    cd15539
    Location:335 → 377
    PHD1_AIRE; PHD finger 1 found in autoimmune regulator (AIRE)
    cd15540
    Location:483 → 519
    PHD2_AIRE; PHD finger 2 found in autoimmune regulator (AIRE)
    pfam03172
    Location:4 → 103
    HSR; HSR domain
    cl02536
    Location:197 → 257
    SAND; SAND domain

  2. XM_028845277.1 → XP_028701110.1  autoimmune regulator isoform X3

    UniProtKB/TrEMBL
    G7MMH4
    Conserved Domains (4) summary
    cd15539
    Location:297 → 339
    PHD1_AIRE; PHD finger 1 found in autoimmune regulator (AIRE)
    cd15540
    Location:445 → 481
    PHD2_AIRE; PHD finger 2 found in autoimmune regulator (AIRE)
    pfam03172
    Location:4 → 103
    HSR; HSR domain
    cl02536
    Location:197 → 257
    SAND; SAND domain

  3. XM_028845276.1 → XP_028701109.1  autoimmune regulator isoform X2

    UniProtKB/TrEMBL
    G7MMH4
    Conserved Domains (4) summary
    cd15539
    Location:298 → 340
    PHD1_AIRE; PHD finger 1 found in autoimmune regulator (AIRE)
    cd15540
    Location:446 → 482
    PHD2_AIRE; PHD finger 2 found in autoimmune regulator (AIRE)
    pfam03172
    Location:4 → 103
    HSR; HSR domain
    cl02536
    Location:197 → 257
    SAND; SAND domain

  4. XM_028845278.1 → XP_028701111.1  autoimmune regulator isoform X4

    UniProtKB/TrEMBL
    F6XB41, G7MMH4
    Related
    ENSMMUP00000005576.4, ENSMMUT00000005921.4
    Conserved Domains (4) summary
    cd15539
    Location:298 → 340
    PHD1_AIRE; PHD finger 1 found in autoimmune regulator (AIRE)
    cd15540
    Location:433 → 469
    PHD2_AIRE; PHD finger 2 found in autoimmune regulator (AIRE)
    pfam03172
    Location:4 → 103
    HSR; HSR domain
    cl02536
    Location:197 → 257
    SAND; SAND domain
Nucleotide Protein
Heading Accession and Version

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