FBXW4 F-box and WD repeat domain containing 4 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: FBXW4provided by VGNC
Official Full Name: F-box and WD repeat domain containing 4provided by VGNC
Primary source: VGNC:VGNC:106048
See related: Ensembl:ENSMMUG00000052198
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	9	NC_041762.1 (102098302..102185686, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	9	NC_027901.1 (97274815..97364727, complement)

Chromosome 9 - NC_041762.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of SCF ubiquitin ligase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: F-box/WD repeat-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001257946.2 → NP_001244875.1 F-box/WD repeat-containing protein 4

See identical proteins and their annotated locations for NP_001244875.1

Status: PROVISIONAL

Source sequence(s)

JU335934

UniProtKB/TrEMBL

F7HD38, H9ZCF3

Related

ENSMMUP00000061753.1, ENSMMUT00000094123.1

Conserved Domains (4) summary

COG2319
Location:156 → 365

WD40; WD40 repeat [General function prediction only]

pfam12937
Location:26 → 69

F-box-like; F-box-like

sd00039
Location:204 → 240

7WD40; WD40 repeat [structural motif]

cl02567
Location:150 → 388

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041762.1 Reference Mmul_10 Primary Assembly

Range

102098302..102185686 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028853483.1 → XP_028709316.1 F-box/WD repeat-containing protein 4 isoform X3

Conserved Domains (2) summary

sd00039
Location:119 → 155

7WD40; WD40 repeat [structural motif]

cl29593
Location:65 → 303

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_015147984.2 → XP_015003470.2 F-box/WD repeat-containing protein 4 isoform X1

UniProtKB/TrEMBL

A0A5F8AGE5

Related

ENSMMUP00000076939.1, ENSMMUT00000093292.1

Conserved Domains (3) summary

sd00039
Location:345 → 377

7WD40; WD40 repeat [structural motif]

pfam12937
Location:207 → 250

F-box-like

cl29593
Location:331 → 556

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_015147985.2 → XP_015003471.2 F-box/WD repeat-containing protein 4 isoform X2

UniProtKB/TrEMBL

A0A5F8AGE5

Conserved Domains (3) summary

sd00039
Location:345 → 377

7WD40; WD40 repeat [structural motif]

pfam12937
Location:207 → 250

F-box-like

cl29593
Location:331 → 522

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_028853484.1 → XP_028709317.1 F-box/WD repeat-containing protein 4 isoform X3

Conserved Domains (2) summary

sd00039
Location:119 → 155

7WD40; WD40 repeat [structural motif]

cl29593
Location:65 → 303

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...