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MARK1 microtubule affinity regulating kinase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 710695, updated on 17-Aug-2024

Summary

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Official Symbol
MARK1provided by VGNC
Official Full Name
microtubule affinity regulating kinase 1provided by VGNC
Primary source
VGNC:VGNC:74658
See related
Ensembl:ENSMMUG00000022288
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MARK1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (78121368..78264953)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (145665558..145809004, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P0 pseudogene Neighboring gene PRELI domain containing protein 3B-like Neighboring gene histone deacetylase 1-like Neighboring gene chromosome 1 C1orf115 homolog Neighboring gene uncharacterized LOC114680575

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tau-protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase MARK1
Names
serine/threonine-protein kinase MARK1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    78121368..78264953
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015115877.2 → XP_014971363.1  serine/threonine-protein kinase MARK1 isoform X1

    UniProtKB/TrEMBL
    F6X739, F6X788
    Related
    ENSMMUP00000029340.4, ENSMMUT00000031356.4
    Conserved Domains (4) summary
    cd12196
    Location:696 → 793
    MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
    smart00220
    Location:60 → 311
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14405
    Location:331 → 371
    UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
    cd14072
    Location:59 → 311
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

  2. XM_015115881.2 → XP_014971367.1  serine/threonine-protein kinase MARK1 isoform X2

    UniProtKB/TrEMBL
    F6X739
    Conserved Domains (4) summary
    cd12196
    Location:695 → 792
    MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
    smart00220
    Location:60 → 311
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14405
    Location:331 → 371
    UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
    cd14072
    Location:59 → 311
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

  3. XM_015115890.2 → XP_014971376.1  serine/threonine-protein kinase MARK1 isoform X4

    UniProtKB/TrEMBL
    F6X739
    Related
    ENSMMUP00000029342.4, ENSMMUT00000031359.4
    Conserved Domains (4) summary
    cd12196
    Location:680 → 777
    MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
    smart00220
    Location:60 → 311
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14405
    Location:331 → 371
    UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
    cd14072
    Location:59 → 311
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

  4. XM_015115885.2 → XP_014971371.1  serine/threonine-protein kinase MARK1 isoform X3

    UniProtKB/TrEMBL
    F6X739
    Conserved Domains (4) summary
    cd12196
    Location:681 → 778
    MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
    smart00220
    Location:60 → 311
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14405
    Location:331 → 371
    UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
    cd14072
    Location:59 → 311
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

  5. XM_015115902.2 → XP_014971388.1  serine/threonine-protein kinase MARK1 isoform X6

    UniProtKB/TrEMBL
    F6X739
    Conserved Domains (4) summary
    cd12196
    Location:586 → 683
    MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
    smart00220
    Location:1 → 201
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14405
    Location:221 → 261
    UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
    cl21453
    Location:1 → 201
    PKc_like; Protein Kinases, catalytic domain

  6. XM_015115895.2 → XP_014971381.1  serine/threonine-protein kinase MARK1 isoform X5

    UniProtKB/TrEMBL
    F6X739
    Conserved Domains (4) summary
    cd12196
    Location:608 → 705
    MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
    smart00220
    Location:15 → 223
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14405
    Location:243 → 283
    UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
    cl21453
    Location:10 → 223
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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