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MID1 midline 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 709683, updated on 17-Aug-2024

Summary

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Official Symbol
MID1provided by VGNC
Official Full Name
midline 1provided by VGNC
Primary source
VGNC:VGNC:74721
See related
Ensembl:ENSMMUG00000020179
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MID1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
16
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (10025730..10416839, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (9518042..9908895, complement)

Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene WWC family member 3 Neighboring gene chloride voltage-gated channel 4 Neighboring gene U6 spliceosomal RNA Neighboring gene Rho GTPase activating protein 6 Neighboring gene holocytochrome c synthase Neighboring gene amelogenin X-linked

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase Midline-1
Names
midline 1 (Opitz/BBB syndrome)
XP_001093502.2
XP_014982415.2
XP_014982416.2
XP_014982417.2
XP_028698130.1
XP_028698131.1
XP_028698132.1
XP_028698133.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041774.1 Reference Mmul_10 Primary Assembly

    Range
    10025730..10416839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028842299.1 → XP_028698132.1  E3 ubiquitin-protein ligase Midline-1 isoform X2

    Conserved Domains (6) summary
    smart00502
    Location:182 → 306
    BBC; B-Box C-terminal domain
    cd00063
    Location:343 → 443
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd12892
    Location:447 → 623
    SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59
    cd16753
    Location:8 → 61
    RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins
    cd19836
    Location:115 → 164
    Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins
    pfam18568
    Location:285 → 336
    COS; TRIM C-terminal subgroup One Signature domain

  2. XM_015126930.2 → XP_014982416.2  E3 ubiquitin-protein ligase Midline-1 isoform X1

    UniProtKB/TrEMBL
    A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86
    Conserved Domains (7) summary
    smart00502
    Location:219 → 344
    BBC; B-Box C-terminal domain
    cd00063
    Location:381 → 481
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd12892
    Location:485 → 661
    SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59
    cd16753
    Location:8 → 61
    RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins
    cd19822
    Location:168 → 214
    Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins
    cd19836
    Location:115 → 164
    Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins
    pfam18568
    Location:323 → 374
    COS; TRIM C-terminal subgroup One Signature domain

  3. XM_015126931.2 → XP_014982417.2  E3 ubiquitin-protein ligase Midline-1 isoform X1

    UniProtKB/TrEMBL
    A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86
    Conserved Domains (7) summary
    smart00502
    Location:219 → 344
    BBC; B-Box C-terminal domain
    cd00063
    Location:381 → 481
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd12892
    Location:485 → 661
    SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59
    cd16753
    Location:8 → 61
    RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins
    cd19822
    Location:168 → 214
    Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins
    cd19836
    Location:115 → 164
    Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins
    pfam18568
    Location:323 → 374
    COS; TRIM C-terminal subgroup One Signature domain

  4. XM_028842298.1 → XP_028698131.1  E3 ubiquitin-protein ligase Midline-1 isoform X1

    UniProtKB/TrEMBL
    A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86
    Conserved Domains (7) summary
    smart00502
    Location:219 → 344
    BBC; B-Box C-terminal domain
    cd00063
    Location:381 → 481
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd12892
    Location:485 → 661
    SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59
    cd16753
    Location:8 → 61
    RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins
    cd19822
    Location:168 → 214
    Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins
    cd19836
    Location:115 → 164
    Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins
    pfam18568
    Location:323 → 374
    COS; TRIM C-terminal subgroup One Signature domain

  5. XM_028842300.1 → XP_028698133.1  E3 ubiquitin-protein ligase Midline-1 isoform X2

    Conserved Domains (6) summary
    smart00502
    Location:182 → 306
    BBC; B-Box C-terminal domain
    cd00063
    Location:343 → 443
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd12892
    Location:447 → 623
    SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59
    cd16753
    Location:8 → 61
    RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins
    cd19836
    Location:115 → 164
    Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins
    pfam18568
    Location:285 → 336
    COS; TRIM C-terminal subgroup One Signature domain

  6. XM_015126929.2 → XP_014982415.2  E3 ubiquitin-protein ligase Midline-1 isoform X1

    UniProtKB/TrEMBL
    A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86
    Conserved Domains (7) summary
    smart00502
    Location:219 → 344
    BBC; B-Box C-terminal domain
    cd00063
    Location:381 → 481
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd12892
    Location:485 → 661
    SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59
    cd16753
    Location:8 → 61
    RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins
    cd19822
    Location:168 → 214
    Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins
    cd19836
    Location:115 → 164
    Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins
    pfam18568
    Location:323 → 374
    COS; TRIM C-terminal subgroup One Signature domain

  7. XM_028842297.1 → XP_028698130.1  E3 ubiquitin-protein ligase Midline-1 isoform X1

    UniProtKB/TrEMBL
    A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86
    Conserved Domains (7) summary
    smart00502
    Location:219 → 344
    BBC; B-Box C-terminal domain
    cd00063
    Location:381 → 481
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd12892
    Location:485 → 661
    SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59
    cd16753
    Location:8 → 61
    RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins
    cd19822
    Location:168 → 214
    Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins
    cd19836
    Location:115 → 164
    Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins
    pfam18568
    Location:323 → 374
    COS; TRIM C-terminal subgroup One Signature domain

  8. XM_001093502.4 → XP_001093502.2  E3 ubiquitin-protein ligase Midline-1 isoform X1

    UniProtKB/TrEMBL
    A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86
    Related
    ENSMMUP00000007446.4, ENSMMUT00000007921.4
    Conserved Domains (7) summary
    smart00502
    Location:219 → 344
    BBC; B-Box C-terminal domain
    cd00063
    Location:381 → 481
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd12892
    Location:485 → 661
    SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59
    cd16753
    Location:8 → 61
    RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins
    cd19822
    Location:168 → 214
    Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins
    cd19836
    Location:115 → 164
    Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins
    pfam18568
    Location:323 → 374
    COS; TRIM C-terminal subgroup One Signature domain
Nucleotide Protein
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