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ACO2 aconitase 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 707441, updated on 17-Aug-2024

Summary

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Official Symbol
ACO2provided by VGNC
Official Full Name
aconitase 2provided by VGNC
Primary source
VGNC:VGNC:69379
See related
Ensembl:ENSMMUG00000001454
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See ACO2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
20
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (9981538..10039834, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (83545554..83606531)

Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene X-ray repair cross complementing 6 Neighboring gene phosphomannomutase 1 Neighboring gene uncharacterized LOC114670348 Neighboring gene cold shock domain containing C2 Neighboring gene RNA polymerase III subunit H Neighboring gene uncharacterized LOC114670349 Neighboring gene PHD finger protein 5A Neighboring gene transducer of ERBB2, 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables aconitate hydratase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
aconitate hydratase, mitochondrial
Names
aconitase 2, mitochondrial
NP_001248093.1
XP_015005884.1
XP_028683137.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261164.2 → NP_001248093.1  aconitate hydratase, mitochondrial

    See identical proteins and their annotated locations for NP_001248093.1

    Status: PROVISIONAL

    Source sequence(s)
    JV047194
    UniProtKB/TrEMBL
    A0A1D5QB91, F7BKH7
    Related
    ENSMMUP00000001942.2, ENSMMUT00000002057.4
    Conserved Domains (3) summary
    cd01584
    Location:95 → 505
    AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
    cd01578
    Location:587 → 735
    AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
    TIGR01340
    Location:45 → 775
    aconitase_mito; aconitate hydratase, mitochondrial

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041763.1 Reference Mmul_10 Primary Assembly

    Range
    9981538..10039834 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015150398.2 → XP_015005884.1  aconitate hydratase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A1D5QB91, A0A5F8AU65
    Related
    ENSMMUP00000080481.1, ENSMMUT00000105367.1
    Conserved Domains (1) summary
    TIGR01340
    Location:45 → 744
    aconitase_mito; aconitate hydratase, mitochondrial

  2. XM_028827304.1 → XP_028683137.1  aconitate hydratase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A1D5QB91, A0A5F8AR81
    Related
    ENSMMUP00000080455.1, ENSMMUT00000105683.1
    Conserved Domains (1) summary
    TIGR01340
    Location:12 → 742
    aconitase_mito; aconitate hydratase, mitochondrial

RNA

  1. XR_001447795.2 RNA Sequence

    Related
    ENSMMUT00000074749.2
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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