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THRB thyroid hormone receptor beta [ Homo sapiens (human) ]

Gene ID: 7068, updated on 11-Apr-2024

Summary

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Official Symbol
THRBprovided by HGNC
Official Full Name
thyroid hormone receptor betaprovided by HGNC
Primary source
HGNC:HGNC:11799
See related
Ensembl:ENSG00000151090 MIM:190160; AllianceGenome:HGNC:11799
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TRb; GRTH; PRTH; THR1; ERBA2; NR1A2; THRB1; THRB2; TRbeta; THRbeta; TRbeta1; C-ERBA-2; THRbeta1; Thrbeta2; C-ERBA-BETA
Summary
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in brain (RPKM 8.1), fat (RPKM 4.3) and 22 other tissues See more
Orthologs
mouse all
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Genomic context

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See THRB in Genome Data Viewer
Location:
3p24.2
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (24117153..24495708, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (24121636..24500130, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (24158644..24537199, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 691 Neighboring gene nucleophosmin 1 pseudogene 23 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr3:24184437-24185636 Neighboring gene MPRA-validated peak4578 silencer Neighboring gene THRB antisense RNA 2 Neighboring gene GATA motif-containing MPRA enhancer 252 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:24401392-24402024 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:24437700-24438265 Neighboring gene Sharpr-MPRA regulatory region 12793 Neighboring gene HNF4 motif-containing MPRA enhancer 120 Neighboring gene ribosomal protein L31 pseudogene 20 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:24538119-24538324 Neighboring gene uncharacterized LOC107986011 Neighboring gene THRB antisense RNA 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:24560666-24561278 Neighboring gene eukaryotic translation initiation factor 3 subunit K pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Atrial Fibrillation with Heart Failure in a Case with Resistance to Thyroid Hormone Due to a Rare Thyroid Hormone Receptor β Gene Mutation. Lai HP, et al. Int J Mol Sci, 2022 Dec 3. PMID 36499571, Free PMC Article
  2. Low THRB (thyroid hormone receptor beta) Promoter Methylation Levels in Peripheral Blood Leukocytes Induced By Systematic Inflammation Are Involved in Low Thyroid Hormone Function in Metabolic Syndrome. Cui B, et al. Hypertension, 2021 Sep. PMID 34397273
  3. Hypercholesterolemia in Two Siblings with Resistance to Thyroid Hormones Due to Disease-Causing Variant in Thyroid Hormone Receptor (THRB) Gene. Pajek M, et al. Medicina (Kaunas), 2020 Dec 15. PMID 33333891, Free PMC Article
  4. Thyroid hormone resistance syndrome with P453T mutation in thyroid hormone receptor β gene: A pedigree report. Yusufu A, et al. Medicine (Baltimore), 2020 Oct 30. PMID 33126322, Free PMC Article
  5. Patients with mutations of the Thyroid hormone beta-receptor show an ADHD-like phenotype for performance monitoring: an electrophysiological study. Uter J, et al. Neuroimage Clin, 2020. PMID 32217468, Free PMC Article

See all (294) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Thyroid hormone Beta receptor agonists for treatment of kidney disease: A promising agent?
    Title: Thyroid hormone Beta receptor agonists for treatment of kidney disease: A promising agent?
  2. Effect of the Fetal THRB Genotype on the Placenta.
    Title: Effect of the Fetal THRB Genotype on the Placenta.
  3. Atrial Fibrillation with Heart Failure in a Case with Resistance to Thyroid Hormone Due to a Rare Thyroid Hormone Receptor beta Gene Mutation.
    Title: Atrial Fibrillation with Heart Failure in a Case with Resistance to Thyroid Hormone Due to a Rare Thyroid Hormone Receptor β Gene Mutation.
  4. Low THRB (thyroid hormone receptor beta) Promoter Methylation Levels in Peripheral Blood Leukocytes Induced By Systematic Inflammation Are Involved in Low Thyroid Hormone Function in Metabolic Syndrome.
    Title: Low THRB (thyroid hormone receptor beta) Promoter Methylation Levels in Peripheral Blood Leukocytes Induced By Systematic Inflammation Are Involved in Low Thyroid Hormone Function in Metabolic Syndrome.
  5. Life Without Thyroid Hormone Receptor.
    Title: Life Without Thyroid Hormone Receptor.
  6. Structural insights revealed by two novel THRB mutations.
    Title: Structural insights revealed by two novel THRB mutations.
  7. Hypercholesterolemia in Two Siblings with Resistance to Thyroid Hormones Due to Disease-Causing Variant in Thyroid Hormone Receptor (THRB) Gene.
    Title: Hypercholesterolemia in Two Siblings with Resistance to Thyroid Hormones Due to Disease-Causing Variant in Thyroid Hormone Receptor (THRB) Gene.
  8. Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival.
    Title: Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival.
  9. Patients with mutations of the Thyroid hormone beta-receptor show an ADHD-like phenotype for performance monitoring: an electrophysiological study.
    Title: Patients with mutations of the Thyroid hormone beta-receptor show an ADHD-like phenotype for performance monitoring: an electrophysiological study.
  10. Characterization of adipogenic, PPARgamma, and TRbeta activities in house dust extracts and their associations with organic contaminants.
    Title: Characterization of adipogenic, PPARγ, and TRβ activities in house dust extracts and their associations with organic contaminants.
Submit: New GeneRIF Correction See all GeneRIFs (164)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Selective pituitary resistance to thyroid hormone
MedGen: C1840364 OMIM: 145650 GeneReviews: Not available
Compare labs
Thyroid hormone resistance, generalized, autosomal dominant
MedGen: C2937288 OMIM: 188570 GeneReviews: Not available
Compare labs
Thyroid hormone resistance, generalized, autosomal recessive
MedGen: C3489796 OMIM: 274300 GeneReviews: Not available
Compare labs

EBI GWAS Catalog

Description
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
EBI GWAS Catalog
Genome-wide association study of hematological and biochemical traits in a Japanese population.
EBI GWAS Catalog
Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease.
EBI GWAS Catalog
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
EBI GWAS Catalog
Seventy-five genetic loci influencing the human red blood cell.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC126109, MGC126110

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding TAS
Traceable Author Statement
more info
 PubMed 
enables DNA-binding transcription factor activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables enzyme binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nuclear receptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific double-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables thyroid hormone binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription coactivator binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to thyroid hormone stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in female courtship behavior IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of female receptivity IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of thyroid hormone mediated signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of heart contraction IEA
Inferred from Electronic Annotation
more info
  
involved_in retinal cone cell apoptotic process IEA
Inferred from Electronic Annotation
more info
  
involved_in retinal cone cell development IEA
Inferred from Electronic Annotation
more info
  
involved_in retinoic acid receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sensory perception of sound IEA
Inferred from Electronic Annotation
more info
  
involved_in thyroid hormone mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in type I pneumocyte differentiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase II transcription regulator complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of chromatin ISA
Inferred from Sequence Alignment
more info
  
located_in nuclear body IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
thyroid hormone receptor beta
Names
nuclear receptor subfamily 1 group A member 2
oncogene ERBA2
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_009159.1 RefSeqGene

    Range
    4973..382670
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_000461.5 → NP_000452.2  thyroid hormone receptor beta isoform a

    See identical proteins and their annotated locations for NP_000452.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (a). Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC098971, AK095776, AW449568, BC028910, BC106929, BP313943, M26747
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Related
    ENSP00000379904.2, ENST00000396671.7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  2. NM_001128176.3 → NP_001121648.1  thyroid hormone receptor beta isoform a

    See identical proteins and their annotated locations for NP_001121648.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC098971, AW449568, AY286468, BC106930, GQ869477
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Related
    ENSP00000348827.4, ENST00000356447.9
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  3. NM_001128177.2 → NP_001121649.1  thyroid hormone receptor beta isoform a

    See identical proteins and their annotated locations for NP_001121649.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC098971, AK095776, AK096628, AW449568, BC028910, M26747
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  4. NM_001252634.2 → NP_001239563.1  thyroid hormone receptor beta isoform a

    See identical proteins and their annotated locations for NP_001239563.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC098971, AK096628, AW449568, GQ869477
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Related
    ENSP00000414444.1, ENST00000416420.5
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  5. NM_001354708.2 → NP_001341637.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  6. NM_001354709.2 → NP_001341638.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  7. NM_001354710.2 → NP_001341639.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  8. NM_001354711.2 → NP_001341640.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  9. NM_001354712.2 → NP_001341641.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Related
    ENSP00000496686.2, ENST00000646209.2
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  10. NM_001354713.2 → NP_001341642.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1-10 all encode the same isoform (a).
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  11. NM_001354714.2 → NP_001341643.1  thyroid hormone receptor beta isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Conserved Domains (2) summary
    cd06935
    Location:185 → 427
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:75 → 161
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  12. NM_001354715.2 → NP_001341644.1  thyroid hormone receptor beta isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Conserved Domains (2) summary
    cd06935
    Location:185 → 427
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:75 → 161
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  13. NM_001374822.1 → NP_001361751.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variants 1-10 and 14-17, encodes isoform a.
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Related
    ENSP00000493709.1, ENST00000645139.1
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  14. NM_001374823.1 → NP_001361752.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 1-10, 13, and 15-17, encodes isoform a.
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Related
    ENSP00000494618.1, ENST00000642307.1
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  15. NM_001374824.1 → NP_001361753.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variants 1-10, 13, 14, 16, and 17, encodes isoform a.
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Related
    ENSP00000496029.1, ENST00000643772.1
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  16. NM_001374825.1 → NP_001361754.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variants 1-10, 13-15, and 17, encodes isoform a.
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Related
    ENSP00000496616.1, ENST00000644321.1
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  17. NM_001374826.1 → NP_001361755.1  thyroid hormone receptor beta isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variants 1-10 and 13-16, encodes isoform a.
    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Consensus CDS
    CCDS2641.1
    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  18. NM_001374827.1 → NP_001361756.1  thyroid hormone receptor beta isoform c

    Status: REVIEWED

    Source sequence(s)
    AC012087, AC093927, AC098971, AC099054
    Conserved Domains (2) summary
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers
    cl11397
    Location:216 → 401
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    24117153..24495708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047448794.1 → XP_047304750.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  2. XM_047448810.1 → XP_047304766.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  3. XM_047448801.1 → XP_047304757.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  4. XM_047448799.1 → XP_047304755.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  5. XM_047448803.1 → XP_047304759.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  6. XM_047448796.1 → XP_047304752.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  7. XM_024453734.2 → XP_024309502.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  8. XM_047448811.1 → XP_047304767.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  9. XM_047448791.1 → XP_047304747.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  10. XM_047448813.1 → XP_047304769.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  11. XM_047448802.1 → XP_047304758.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  12. XM_047448807.1 → XP_047304763.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  13. XM_047448798.1 → XP_047304754.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  14. XM_047448789.1 → XP_047304745.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  15. XM_047448805.1 → XP_047304761.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  16. XM_047448817.1 → XP_047304773.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  17. XM_047448812.1 → XP_047304768.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  18. XM_047448793.1 → XP_047304749.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  19. XM_047448806.1 → XP_047304762.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  20. XM_047448792.1 → XP_047304748.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  21. XM_047448809.1 → XP_047304765.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  22. XM_047448808.1 → XP_047304764.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  23. XM_017007113.2 → XP_016862602.1  thyroid hormone receptor beta isoform X2

    Conserved Domains (2) summary
    cd06935
    Location:185 → 427
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:75 → 161
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  24. XM_011534050.3 → XP_011532352.1  thyroid hormone receptor beta isoform X1

    See identical proteins and their annotated locations for XP_011532352.1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  25. XM_047448800.1 → XP_047304756.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  26. XM_047448818.1 → XP_047304774.1  thyroid hormone receptor beta isoform X2

  27. XM_011534047.4 → XP_011532349.1  thyroid hormone receptor beta isoform X1

    See identical proteins and their annotated locations for XP_011532349.1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  28. XM_047448814.1 → XP_047304770.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  29. XM_047448815.1 → XP_047304771.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  30. XM_047448804.1 → XP_047304760.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  31. XM_047448795.1 → XP_047304751.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  32. XM_047448790.1 → XP_047304746.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  33. XM_047448797.1 → XP_047304753.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Related
    ENSP00000496509.1, ENST00000646432.1

  34. XM_047448816.1 → XP_047304772.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  35. XM_024453737.2 → XP_024309505.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    24121636..24500130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054347675.1 → XP_054203650.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  2. XM_054347692.1 → XP_054203667.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  3. XM_054347682.1 → XP_054203657.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  4. XM_054347680.1 → XP_054203655.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  5. XM_054347684.1 → XP_054203659.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  6. XM_054347677.1 → XP_054203652.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  7. XM_054347670.1 → XP_054203645.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  8. XM_054347693.1 → XP_054203668.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  9. XM_054347672.1 → XP_054203647.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  10. XM_054347695.1 → XP_054203670.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  11. XM_054347683.1 → XP_054203658.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  12. XM_054347687.1 → XP_054203662.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  13. XM_054347679.1 → XP_054203654.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  14. XM_054347669.1 → XP_054203644.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  15. XM_054347686.1 → XP_054203661.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  16. XM_054347701.1 → XP_054203676.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  17. XM_054347694.1 → XP_054203669.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  18. XM_054347674.1 → XP_054203649.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  19. XM_054347688.1 → XP_054203663.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  20. XM_054347673.1 → XP_054203648.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  21. XM_054347690.1 → XP_054203665.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  22. XM_054347689.1 → XP_054203664.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  23. XM_054347703.1 → XP_054203678.1  thyroid hormone receptor beta isoform X2

  24. XM_054347691.1 → XP_054203666.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  25. XM_054347681.1 → XP_054203656.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  26. XM_054347702.1 → XP_054203677.1  thyroid hormone receptor beta isoform X2

  27. XM_054347668.1 → XP_054203643.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  28. XM_054347699.1 → XP_054203674.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  29. XM_054347696.1 → XP_054203671.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  30. XM_054347698.1 → XP_054203673.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  31. XM_054347685.1 → XP_054203660.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  32. XM_054347676.1 → XP_054203651.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  33. XM_054347671.1 → XP_054203646.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  34. XM_054347678.1 → XP_054203653.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  35. XM_054347700.1 → XP_054203675.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7

  36. XM_054347697.1 → XP_054203672.1  thyroid hormone receptor beta isoform X1

    UniProtKB/Swiss-Prot
    B3KU79, P10828, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
    UniProtKB/TrEMBL
    A0A024R2I8, F1D8N7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P10828.2 GenPept UniProtKB/Swiss-Prot:P10828

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