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Tmem144 transmembrane protein 144 [ Mus musculus (house mouse) ]

Gene ID: 70652, updated on 2-Nov-2024

Summary

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Official Symbol
Tmem144provided by MGI
Official Full Name
transmembrane protein 144provided by MGI
Primary source
MGI:MGI:1917902
See related
Ensembl:ENSMUSG00000027956 AllianceGenome:MGI:1917902
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110057I03Rik; 5730537D05Rik
Summary
Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be located in membrane. Orthologous to human TMEM144 (transmembrane protein 144). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 23.7), placenta adult (RPKM 5.3) and 6 other tissues See more
Orthologs
human all
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Genomic context

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See Tmem144 in Genome Data Viewer
Location:
3 E3; 3 35.07 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (79719871..79760093, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (79812564..79852787, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930579G24 gene Neighboring gene STARR-seq mESC enhancer starr_08007 Neighboring gene VISTA enhancer mm1650 Neighboring gene relaxin/insulin-like family peptide receptor 1 Neighboring gene STARR-seq mESC enhancer starr_08009 Neighboring gene STARR-positive B cell enhancer ABC_E3438 Neighboring gene predicted gene, 26420 Neighboring gene STARR-seq mESC enhancer starr_08010 Neighboring gene STARR-seq mESC enhancer starr_08011 Neighboring gene STARR-seq mESC enhancer starr_08012 Neighboring gene golgi associated kinase 1B Neighboring gene STARR-seq mESC enhancer starr_08013 Neighboring gene VISTA enhancer mm1052 Neighboring gene STARR-seq mESC enhancer starr_08014 Neighboring gene STARR-seq mESC enhancer starr_08015 Neighboring gene RIKEN cDNA A330069K06 gene Neighboring gene STARR-seq mESC enhancer starr_08016 Neighboring gene eukaryotic translation initiation factor 3, subunit M pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables carbohydrate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in carbohydrate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 144

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001379542.1 → NP_001366471.1  transmembrane protein 144 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variants 1 and 3, encodes isoform a.
    Source sequence(s)
    AC159281
    UniProtKB/Swiss-Prot
    Q8VEH0, Q9CYC7
    Related
    ENSMUSP00000127837.2, ENSMUST00000168038.8
    Conserved Domains (1) summary
    cl19288
    Location:9 → 347
    RhaT; L-rhamnose-proton symport protein (RhaT)

  2. NM_001379543.1 → NP_001366472.1  transmembrane protein 144 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variants 1 and 2, encodes isoform a.
    Source sequence(s)
    AC159281
    UniProtKB/Swiss-Prot
    Q8VEH0, Q9CYC7
    Conserved Domains (1) summary
    cl19288
    Location:9 → 347
    RhaT; L-rhamnose-proton symport protein (RhaT)

  3. NM_001379544.1 → NP_001366473.1  transmembrane protein 144 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC159281
    Conserved Domains (1) summary
    cl19288
    Location:1 → 125
    RhaT; L-rhamnose-proton symport protein (RhaT)

  4. NM_027495.5 → NP_081771.2  transmembrane protein 144 isoform a

    See identical proteins and their annotated locations for NP_081771.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1-3 all encode the same isoform (a).
    Source sequence(s)
    AC159281
    Consensus CDS
    CCDS17421.1
    UniProtKB/Swiss-Prot
    Q8VEH0, Q9CYC7
    Related
    ENSMUSP00000029568.2, ENSMUST00000029568.7
    Conserved Domains (1) summary
    cl19288
    Location:9 → 347
    RhaT; L-rhamnose-proton symport protein (RhaT)

RNA

  1. NR_166772.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC159281

  2. NR_166773.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC159281

  3. NR_166774.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC159281

  4. NR_166775.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC159281

  5. NR_166776.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC159281

  6. NR_166777.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC159281

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    79719871..79760093 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502059.5 → XP_006502122.1  transmembrane protein 144 isoform X1

    See identical proteins and their annotated locations for XP_006502122.1

    UniProtKB/Swiss-Prot
    Q8VEH0, Q9CYC7
    Conserved Domains (1) summary
    cl19288
    Location:9 → 347
    RhaT; L-rhamnose-proton symport protein (RhaT)

  2. XM_006502058.5 → XP_006502121.1  transmembrane protein 144 isoform X1

    See identical proteins and their annotated locations for XP_006502121.1

    UniProtKB/Swiss-Prot
    Q8VEH0, Q9CYC7
    Conserved Domains (1) summary
    cl19288
    Location:9 → 347
    RhaT; L-rhamnose-proton symport protein (RhaT)

  3. XM_030252816.2 → XP_030108676.1  transmembrane protein 144 isoform X2

    Conserved Domains (1) summary
    cl19288
    Location:1 → 186
    RhaT; L-rhamnose-proton symport protein (RhaT)

  4. XM_036163306.1 → XP_036019199.1  transmembrane protein 144 isoform X1

    UniProtKB/Swiss-Prot
    Q8VEH0, Q9CYC7
    Conserved Domains (1) summary
    cl19288
    Location:9 → 347
    RhaT; L-rhamnose-proton symport protein (RhaT)

  5. XM_036163305.1 → XP_036019198.1  transmembrane protein 144 isoform X1

    UniProtKB/Swiss-Prot
    Q8VEH0, Q9CYC7
    Conserved Domains (1) summary
    cl19288
    Location:9 → 347
    RhaT; L-rhamnose-proton symport protein (RhaT)

RNA

  1. XR_001783743.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VEH0.1 GenPept UniProtKB/Swiss-Prot:Q8VEH0

Gene LinkOut

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