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EDEM2 ER degradation enhancing alpha-mannosidase like protein 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 706150, updated on 17-Aug-2024

Summary

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Official Symbol
EDEM2provided by VGNC
Official Full Name
ER degradation enhancing alpha-mannosidase like protein 2provided by VGNC
Primary source
VGNC:VGNC:72050
Locus tag
EGK_02472
See related
Ensembl:ENSMMUG00000010032
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See EDEM2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (70319902..70353084, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (28985811..29018919)

Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene myosin heavy chain 7B Neighboring gene microRNA mir-499 Neighboring gene transient receptor potential cation channel subfamily C member 4 associated protein Neighboring gene small nucleolar RNA SNORD56 Neighboring gene uncharacterized LOC107000422 Neighboring gene protein C receptor Neighboring gene matrix metallopeptidase 24 Neighboring gene MMP24 opposite strand

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endoplasmic reticulum mannose trimming IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mannose trimming involved in glycoprotein ERAD pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ER degradation-enhancing alpha-mannosidase-like protein 2
Names
ER degradation-enhancing alpha-mannosidase-like 2
NP_001247965.1
XP_028683128.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261036.1 → NP_001247965.1  ER degradation-enhancing alpha-mannosidase-like protein 2 precursor

    See identical proteins and their annotated locations for NP_001247965.1

    Status: PROVISIONAL

    Source sequence(s)
    JU472490
    UniProtKB/TrEMBL
    A0A8J8Y7A5, F6Q1A3, G7N500, H9ER27
    Related
    ENSMMUP00000013112.4, ENSMMUT00000014003.4
    Conserved Domains (1) summary
    pfam01532
    Location:42 → 480
    Glyco_hydro_47; Glycosyl hydrolase family 47

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041763.1 Reference Mmul_10 Primary Assembly

    Range
    70319902..70353084 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028827295.1 → XP_028683128.1  ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1

    UniProtKB/TrEMBL
    F7AUH8
    Related
    ENSMMUP00000037782.3, ENSMMUT00000044763.3
    Conserved Domains (1) summary
    pfam01532
    Location:36 → 443
    Glyco_hydro_47; Glycosyl hydrolase family 47
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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