ITGA2 integrin subunit alpha 2 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: ITGA2provided by VGNC
Official Full Name: integrin subunit alpha 2provided by VGNC
Primary source: VGNC:VGNC:73775
Locus tag: EGK_16473
See related: Ensembl:ENSMMUG00000020448
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 6

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	6	NC_041759.1 (51271828..51377627)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	6	NC_027898.1 (53886584..53987861)

Chromosome 6 - NC_041759.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

SHGC-142139 (e-PCR)
- UniSTS:171280

D5S2427 (e-PCR)
- UniSTS:8728

D5S623 (e-PCR), detects polymorphism
- UniSTS:79945

ITGA2b (e-PCR)
- UniSTS:479884

D5S2773 (e-PCR)
- UniSTS:473841

Itga2 (e-PCR), detects polymorphism
- UniSTS:143609

Itga2 (e-PCR), detects polymorphism
- UniSTS:143611

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables integrin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell adhesion mediated by integrin	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell-cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell-matrix adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in integrin-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of integrin complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: integrin alpha-2

Names: Platelet membrane glycoprotein Ia; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001260822.1 → NP_001247751.1 integrin alpha-2 precursor

See identical proteins and their annotated locations for NP_001247751.1

Status: PROVISIONAL

Source sequence(s)

JU334386

UniProtKB/TrEMBL

A0A1D5QY01, A0A5S6RAX0, A0A8J8Y857, F6W6R0, G7MTQ0

Related

ENSMMUP00000052931.2, ENSMMUT00000059183.2

Conserved Domains (3) summary

smart00191
Location:551 → 604

Int_alpha; Integrin alpha (beta-propellor repeats)

cd01469
Location:173 → 353

vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...

pfam08441
Location:655 → 1059

Integrin_alpha2; Integrin alpha