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PKD2 polycystin 2, transient receptor potential cation channel [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 702179, updated on 17-Aug-2024

Summary

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Official Symbol
PKD2provided by VGNC
Official Full Name
polycystin 2, transient receptor potential cation channelprovided by VGNC
Primary source
VGNC:VGNC:100262
See related
Ensembl:ENSMMUG00000008795
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PKD2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
15
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (86399578..86470892)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (86364051..86435312)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene U1 spliceosomal RNA Neighboring gene secreted phosphoprotein 1 Neighboring gene uncharacterized LOC114678352 Neighboring gene ATP binding cassette subfamily G member 2 Neighboring gene U6 spliceosomal RNA Neighboring gene U6atac minor spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables muscle alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of mechanical stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
polycystin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    86399578..86470892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028848611.1 → XP_028704444.1  polycystin-2 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZNH5, A0A5F8AFI1
    Related
    ENSMMUP00000076629.1, ENSMMUT00000102540.1
    Conserved Domains (2) summary
    pfam08016
    Location:268 → 632
    PKD_channel; Polycystin cation channel
    cl08302
    Location:677 → 723
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. XM_001099242.4 → XP_001099242.2  polycystin-2 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZNH5, F7F220
    Related
    ENSMMUP00000011535.4, ENSMMUT00000012297.4
    Conserved Domains (2) summary
    pfam08016
    Location:268 → 688
    PKD_channel; Polycystin cation channel
    cl08302
    Location:733 → 779
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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