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DEGS1 delta 4-desaturase, sphingolipid 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 702128, updated on 17-Aug-2024

Summary

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Official Symbol
DEGS1provided by VGNC
Official Full Name
delta 4-desaturase, sphingolipid 1provided by VGNC
Primary source
VGNC:VGNC:71620
See related
Ensembl:ENSMMUG00000002400
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DEGS1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (81638838..81648960)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (142241073..142250552, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene translocase of inner mitochondrial membrane 8 homolog B Neighboring gene F-box protein 28 Neighboring gene uncharacterized LOC106993365 Neighboring gene nuclear VCP like Neighboring gene microRNA mir-320b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sphingolipid delta-4 desaturase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingolipid delta(4)-desaturase DES1
Names
degenerative spermatocyte homolog 1, lipid desaturase
NP_001252935.1
XP_028693334.1
XP_028693362.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266006.1 → NP_001252935.1  sphingolipid delta(4)-desaturase DES1

    See identical proteins and their annotated locations for NP_001252935.1

    Status: PROVISIONAL

    Source sequence(s)
    JV045802
    UniProtKB/TrEMBL
    F6PPX9, G7MEG8
    Related
    ENSMMUP00000003220.2, ENSMMUT00000003410.4
    Conserved Domains (3) summary
    PLN02579
    Location:5 → 314
    PLN02579; sphingolipid delta-4 desaturase
    cd03508
    Location:26 → 315
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
    pfam08557
    Location:6 → 42
    Lipid_DES; Sphingolipid Delta4-desaturase (DES)

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    81638838..81648960
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028837501.1 → XP_028693334.1  sphingolipid delta(4)-desaturase DES1 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZM44, G7MEG8
    Related
    ENSMMUP00000065685.1, ENSMMUT00000104847.1
    Conserved Domains (1) summary
    cd03508
    Location:17 → 304
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...

  2. XM_028837529.1 → XP_028693362.1  sphingolipid delta(4)-desaturase DES1 isoform X2

    UniProtKB/TrEMBL
    G7MEG8
    Conserved Domains (1) summary
    cd03508
    Location:1 → 279
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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