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IL1RN interleukin 1 receptor antagonist [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 701658, updated on 17-Aug-2024

Summary

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Official Symbol
IL1RNprovided by VGNC
Official Full Name
interleukin 1 receptor antagonistprovided by VGNC
Primary source
VGNC:VGNC:73723
See related
Ensembl:ENSMMUG00000013014
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See IL1RN in Genome Data Viewer
Location:
chromosome: 13
Exon count:
6
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (16298692..16314460)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (108115924..108131728)

Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene interleukin 1 family member 10 Neighboring gene U6 spliceosomal RNA Neighboring gene pleckstrin and Sec7 domain containing 4 Neighboring gene paired box 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels. Rafiq S, et al. Genes Immun, 2007 Jun. PMID 17443229
  2. Association between the interleukin-1 receptor antagonist gene and negative symptom improvement during antipsychotic treatment. Mata I, et al. Am J Med Genet B Neuropsychiatr Genet, 2006 Dec 5. PMID 16921503
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The variable number of tandem repeats polymorphism in the IL-1RN gene may be a useful predictor of negative symptom improvement in schizophrenic patients treated with antipsychotic drugs.
    Title: Association between the interleukin-1 receptor antagonist gene and negative symptom improvement during antipsychotic treatment.
  2. common variation across the IL-1RN gene is strongly associated with IL-1RA levels.
    Title: Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-1 receptor antagonist activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-1 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inflammatory response to antigenic stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of interleukin-1-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-1 receptor antagonist protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041766.1 Reference Mmul_10 Primary Assembly

    Range
    16298692..16314460
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015113137.2 → XP_014968623.1  interleukin-1 receptor antagonist protein isoform X2

    UniProtKB/TrEMBL
    F7HP64
    Related
    ENSMMUP00000017085.4, ENSMMUT00000018251.4
    Conserved Domains (1) summary
    smart00125
    Location:16 → 156
    IL1; Interleukin-1 homologues

  2. XM_015113138.2 → XP_014968624.1  interleukin-1 receptor antagonist protein isoform X3

    Conserved Domains (1) summary
    smart00125
    Location:1 → 140
    IL1; Interleukin-1 homologues

  3. XM_001091833.4 → XP_001091833.1  interleukin-1 receptor antagonist protein isoform X1

    See identical proteins and their annotated locations for XP_001091833.1

    UniProtKB/TrEMBL
    A0A1D5Q1Y0, F7HP64
    Related
    ENSMMUP00000042042.2, ENSMMUT00000067411.2
    Conserved Domains (1) summary
    smart00125
    Location:34 → 174
    IL1; Interleukin-1 homologues
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials