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CRK CRK proto-oncogene, adaptor protein [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 701185, updated on 17-Aug-2024

Summary

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Official Symbol
CRKprovided by VGNC
Official Full Name
CRK proto-oncogene, adaptor proteinprovided by VGNC
Primary source
VGNC:VGNC:99140
See related
Ensembl:ENSMMUG00000040390
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See CRK in Genome Data Viewer
Location:
chromosome: 16
Exon count:
4
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (1273275..1308632, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (1302380..1338204, complement)

Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene trafficking regulator of GLUT4 (SLC2A4) 1 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon Neighboring gene myosin IC Neighboring gene uncharacterized LOC114673032 Neighboring gene inositol polyphosphate-5-phosphatase K

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adapter molecule crk

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041769.1 Reference Mmul_10 Primary Assembly

    Range
    1273275..1308632 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015118183.2 → XP_014973669.1  adapter molecule crk isoform X3

    UniProtKB/TrEMBL
    H9FQ53
    Conserved Domains (2) summary
    cd09926
    Location:5 → 122
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:135 → 189
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

  2. XM_002808109.3 → XP_002808155.2  adapter molecule crk isoform X1

    UniProtKB/TrEMBL
    H9FQ57
    Related
    ENSMMUP00000042452.1, ENSMMUT00000058676.2
    Conserved Domains (3) summary
    cd09926
    Location:5 → 122
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:135 → 189
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:237 → 293
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

  3. XM_028835845.1 → XP_028691678.1  adapter molecule crk isoform X2

    UniProtKB/TrEMBL
    G7NHL5
    Conserved Domains (3) summary
    cd11758
    Location:79 → 133
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:181 → 237
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cl15255
    Location:22 → 66
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein
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