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Ceacam13 CEA cell adhesion molecule 13 [ Mus musculus (house mouse) ]

Gene ID: 69785, updated on 2-Nov-2024

Summary

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Official Symbol
Ceacam13provided by MGI
Official Full Name
CEA cell adhesion molecule 13provided by MGI
Primary source
MGI:MGI:1917035
See related
Ensembl:ENSMUSG00000057195 AllianceGenome:MGI:1917035
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1600012K03Rik; 1600025J19Rik
Summary
Predicted to be involved in T cell activation and immune response. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward placenta adult (RPKM 72.5) See more
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Genomic context

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See Ceacam13 in Genome Data Viewer
Location:
7 A2; 7 9.15 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (17743814..17753145)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (18009889..18019220)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CEA cell adhesion molecule 11 Neighboring gene MHC I like leukocyte 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18161 Neighboring gene eukaryotic translation initiation factor pseudogene Neighboring gene CEA cell adhesion molecule 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. Zebhauser R, et al. Genomics, 2005 Nov. PMID 16139472
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Clone Names

  • MGC117613

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
carcinoembryonic antigen-related cell adhesion molecule 13
Names
CEA-related cell adhesion molecule 13
Ceacam13-C1
Ceacam13-C2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027210.3 → NP_081486.1  carcinoembryonic antigen-related cell adhesion molecule 13 isoform 1 precursor

    See identical proteins and their annotated locations for NP_081486.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes isoform 1. Isoforms 1 and 2 are the same length and differ only in their last two aa.
    Source sequence(s)
    AK005430, BY705748
    Consensus CDS
    CCDS39790.1
    UniProtKB/TrEMBL
    Q9DAY4
    Related
    ENSMUSP00000104128.2, ENSMUST00000108488.7
    Conserved Domains (2) summary
    cd05774
    Location:36 → 140
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
    cl11960
    Location:156 → 260
    Ig; Immunoglobulin domain

  2. NM_028171.2 → NP_082447.1  carcinoembryonic antigen-related cell adhesion molecule 13 isoform 2 precursor

    See identical proteins and their annotated locations for NP_082447.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) encodes isoform 2 and differs in the 3' UTR and coding sequence compared to variant 1. Isoforms 1 and 2 are the same length and differ only in their last two aa.
    Source sequence(s)
    AK005537
    Consensus CDS
    CCDS20866.1
    UniProtKB/TrEMBL
    Q9DAT7
    Related
    ENSMUSP00000080404.7, ENSMUST00000081703.8
    Conserved Domains (2) summary
    cd05774
    Location:36 → 140
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
    cl11960
    Location:156 → 260
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    17743814..17753145
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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