Camsap3 calmodulin regulated spectrin-associated protein family, member 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Camsap3provided by MGI
Official Full Name: calmodulin regulated spectrin-associated protein family, member 3provided by MGI
Primary source: MGI:MGI:1916947
See related: Ensembl:ENSMUSG00000044433 AllianceGenome:MGI:1916947
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Nezha; Kiaa1543; 2310057J16Rik
Summary: Enables microtubule minus-end binding activity. Involved in several processes, including establishment of epithelial cell apical/basal polarity; establishment or maintenance of microtubule cytoskeleton polarity; and regulation of microtubule polymerization. Acts upstream of or within in utero embryonic development. Located in axoneme; ciliary basal body; and motile cilium. Colocalizes with microtubule minus-end. Is expressed in brain and lung epithelium. Orthologous to human CAMSAP3 (calmodulin regulated spectrin associated protein family member 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in colon adult (RPKM 25.0), small intestine adult (RPKM 23.5) and 23 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8 A1.1; 8 1.92 cM

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (3637237..3659075)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (3587237..3609075)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Paracingulin recruits CAMSAP3 to tight junctions and regulates microtubule and polarized epithelial cell organization.
Title: Paracingulin recruits CAMSAP3 to tight junctions and regulates microtubule and polarized epithelial cell organization.
Tracheal motile cilia in mice require CAMSAP3 for the formation of central microtubule pair and coordinated beating.
Title: Tracheal motile cilia in mice require CAMSAP3 for the formation of central microtubule pair and coordinated beating.
Cyst formation in proximal renal tubules caused by dysfunction of the microtubule minus-end regulator CAMSAP3.
Title: Cyst formation in proximal renal tubules caused by dysfunction of the microtubule minus-end regulator CAMSAP3.
CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains.
Title: CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains.
Intercellular and intracellular cilia orientation is coordinated by CELSR1 and CAMSAP3 in oviduct multi-ciliated cells.
Title: Intercellular and intracellular cilia orientation is coordinated by CELSR1 and CAMSAP3 in oviduct multi-ciliated cells.
CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia.
Title: CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia.
Findings suggest that CAMSAP3 functions to protect lung carcinoma cells against EMT by suppressing Akt activity via microtubule regulation and that CAMSAP3 loss promotes EMT in these cells.
Title: Loss of CAMSAP3 promotes EMT via the modification of microtubule-Akt machinery.
maintains neuronal polarity through regulation of microtubule stability
Title: CAMSAP3 maintains neuronal polarity through regulation of microtubule stability.
data suggest that CDH23-C is a CAMSAP3/Marshalin-binding protein that can modify MT networks indirectly through its interaction with CAMSAP3/Marshalin.
Title: Cadherin 23-C Regulates Microtubule Networks by Modifying CAMSAP3's Function.
CAMSAP3 precisely coordinates with dynein and katanin to regulate the microtubule detachment process.
Title: CAMSAP3 accumulates in the pericentrosomal area and accompanies microtubule release from the centrosome via katanin.

Submit: New GeneRIF Correction See all GeneRIFs (13)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (3) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables actin filament binding	ISO Inferred from Sequence Orthology more info
enables actin filament binding	ISS Inferred from Sequence or Structural Similarity more info
enables calmodulin binding	IEA Inferred from Electronic Annotation more info
enables microtubule minus-end binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule minus-end binding	IDA Inferred from Direct Assay more info	PubMed
enables microtubule minus-end binding	ISO Inferred from Sequence Orthology more info
enables microtubule minus-end binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables spectrin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cilium movement	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cytoplasmic microtubule organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in embryo development ending in birth or egg hatching	IDA Inferred from Direct Assay more info	PubMed
involved_in epithelial cell-cell adhesion	ISO Inferred from Sequence Orthology more info
involved_in epithelial cell-cell adhesion	ISS Inferred from Sequence or Structural Similarity more info
involved_in establishment of epithelial cell apical/basal polarity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in establishment of epithelial cell apical/basal polarity	ISO Inferred from Sequence Orthology more info
involved_in establishment of epithelial cell apical/basal polarity	ISS Inferred from Sequence or Structural Similarity more info
involved_in establishment or maintenance of microtubule cytoskeleton polarity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in establishment or maintenance of microtubule cytoskeleton polarity	ISO Inferred from Sequence Orthology more info
involved_in establishment or maintenance of microtubule cytoskeleton polarity	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within in utero embryonic development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule anchoring	ISO Inferred from Sequence Orthology more info
involved_in microtubule anchoring	ISS Inferred from Sequence or Structural Similarity more info
involved_in microtubule cytoskeleton organization	IDA Inferred from Direct Assay more info	PubMed
involved_in microtubule cytoskeleton organization	ISO Inferred from Sequence Orthology more info
involved_in microtubule cytoskeleton organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of microtubule depolymerization	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuron projection development	IEA Inferred from Electronic Annotation more info
involved_in protein transport along microtubule	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of Golgi organization	ISO Inferred from Sequence Orthology more info
involved_in regulation of Golgi organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of cell migration	ISO Inferred from Sequence Orthology more info
involved_in regulation of cell migration	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of focal adhesion assembly	ISO Inferred from Sequence Orthology more info
involved_in regulation of focal adhesion assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of microtubule cytoskeleton organization	ISO Inferred from Sequence Orthology more info
involved_in regulation of microtubule cytoskeleton organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of microtubule polymerization	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of microtubule polymerization	ISO Inferred from Sequence Orthology more info
involved_in regulation of microtubule polymerization	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of organelle organization	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of organelle organization	ISO Inferred from Sequence Orthology more info
involved_in zonula adherens maintenance	ISO Inferred from Sequence Orthology more info
involved_in zonula adherens maintenance	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in axoneme	IDA Inferred from Direct Assay more info	PubMed
located_in centrosome	IEA Inferred from Electronic Annotation more info
colocalizes_with centrosome	ISO Inferred from Sequence Orthology more info
located_in ciliary basal body	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in microtubule cytoskeleton	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with microtubule minus-end	IBA Inferred from Biological aspect of Ancestor more info
colocalizes_with microtubule minus-end	IDA Inferred from Direct Assay more info	PubMed
located_in microtubule minus-end	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with microtubule minus-end	ISO Inferred from Sequence Orthology more info
located_in motile cilium	IDA Inferred from Direct Assay more info	PubMed
located_in zonula adherens	ISO Inferred from Sequence Orthology more info
located_in zonula adherens	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: calmodulin-regulated spectrin-associated protein 3

Names: marshalin; protein Nezha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001163749.1 → NP_001157221.1 calmodulin-regulated spectrin-associated protein 3 isoform 1

See identical proteins and their annotated locations for NP_001157221.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) lacks two exons and uses an alternate in-frame splice site in the 5' coding region compared to variant 3. The encoded isoform (1) is shorter than isoform 3.

Source sequence(s)

AK081728, BC043081, CD349198, CO042496

Consensus CDS

CCDS52469.1

UniProtKB/Swiss-Prot

Q80VC9

Related

ENSMUSP00000125993.2, ENSMUST00000171962.3

Conserved Domains (3) summary

pfam08683
Location:1114 → 1232

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:214 → 296

CAMSAP_CH; CAMSAP CH domain

pfam17095
Location:588 → 645

CAMSAP_CC1; Spectrin-binding region of Ca2+-Calmodulin
NM_001347111.1 → NP_001334040.1 calmodulin-regulated spectrin-associated protein 3 isoform 3

Status: VALIDATED

Description

Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).

Source sequence(s)

AC170806, CO042496, KC426931

Consensus CDS

CCDS85488.1

UniProtKB/Swiss-Prot

Q80VC9

Related

ENSMUSP00000146896.2, ENSMUST00000207432.2
NM_001347112.1 → NP_001334041.1 calmodulin-regulated spectrin-associated protein 3 isoform 4

Status: VALIDATED

Description

Transcript Variant: This variant (4) lacks an in-frame exon in the 5' coding region compared to variant 3. The encoded isoform (4) is shorter than isoform 3.

Source sequence(s)

AC170806, CO042496, KC426933

Consensus CDS

CCDS85490.1

UniProtKB/Swiss-Prot

Q80VC9

Related

ENSMUSP00000146852.2, ENSMUST00000207077.2
NM_001347113.1 → NP_001334042.1 calmodulin-regulated spectrin-associated protein 3 isoform 5

Status: VALIDATED

Description

Transcript Variant: This variant (5) lacks an in-frame exon in the 5' coding region compared to variant 3. The encoded isoform (5) is shorter than isoform 3.

Source sequence(s)

AC170806, CO042496, KC426935

Consensus CDS

CCDS85489.1

UniProtKB/Swiss-Prot

Q80VC9

Related

ENSMUSP00000146772.2, ENSMUST00000207970.2
NM_001363239.1 → NP_001350168.1 calmodulin-regulated spectrin-associated protein 3 isoform 6

Status: VALIDATED

Source sequence(s)

AC170806

Conserved Domains (6) summary

smart01051
Location:1140 → 1268

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam08580
Location:398 → 618

KAR9; Yeast cortical protein KAR9

pfam11971
Location:241 → 323

CAMSAP_CH; CAMSAP CH domain

pfam17095
Location:615 → 672

CAMSAP_CC1; Spectrin-binding region of Ca2+-Calmodulin

cl25548
Location:899 → 967

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:922 → 1020

SMC_N; RecF/RecN/SMC N terminal domain
NM_001363240.1 → NP_001350169.1 calmodulin-regulated spectrin-associated protein 3 isoform 7

Status: VALIDATED

Source sequence(s)

AC170806

Conserved Domains (6) summary

smart01051
Location:1129 → 1257

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam08580
Location:387 → 607

KAR9; Yeast cortical protein KAR9

pfam11971
Location:230 → 312

CAMSAP_CH; CAMSAP CH domain

pfam17095
Location:604 → 661

CAMSAP_CC1; Spectrin-binding region of Ca2+-Calmodulin

cl25548
Location:888 → 956

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:911 → 1009

SMC_N; RecF/RecN/SMC N terminal domain
NM_001363241.1 → NP_001350170.1 calmodulin-regulated spectrin-associated protein 3 isoform 8

Status: VALIDATED

Source sequence(s)

AC170806

Conserved Domains (6) summary

smart01051
Location:1124 → 1252

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam08580
Location:382 → 602

KAR9; Yeast cortical protein KAR9

pfam11971
Location:225 → 307

CAMSAP_CH; CAMSAP CH domain

pfam17095
Location:599 → 656

CAMSAP_CC1; Spectrin-binding region of Ca2+-Calmodulin

cl25548
Location:883 → 951

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:906 → 1004

SMC_N; RecF/RecN/SMC N terminal domain
NM_001363242.1 → NP_001350171.1 calmodulin-regulated spectrin-associated protein 3 isoform 9

Status: VALIDATED

Source sequence(s)

AC170806

Conserved Domains (5) summary

smart01051
Location:724 → 852

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:241 → 323

CAMSAP_CH; CAMSAP CH domain

cl25548
Location:483 → 551

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:506 → 604

SMC_N; RecF/RecN/SMC N terminal domain

cl28087
Location:355 → 581

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
NM_001363243.1 → NP_001350172.1 calmodulin-regulated spectrin-associated protein 3 isoform 10

Status: VALIDATED

Source sequence(s)

AC170806

Conserved Domains (5) summary

smart01051
Location:723 → 851

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:241 → 323

CAMSAP_CH; CAMSAP CH domain

cl25548
Location:482 → 550

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:505 → 603

SMC_N; RecF/RecN/SMC N terminal domain

cl28087
Location:377 → 580

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
NM_001363244.1 → NP_001350173.1 calmodulin-regulated spectrin-associated protein 3 isoform 11

Status: VALIDATED

Source sequence(s)

AC170806

Conserved Domains (5) summary

smart01051
Location:713 → 841

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:230 → 312

CAMSAP_CH; CAMSAP CH domain

cl25548
Location:472 → 540

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:495 → 593

SMC_N; RecF/RecN/SMC N terminal domain

cl28087
Location:344 → 570

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
NM_001363245.1 → NP_001350174.1 calmodulin-regulated spectrin-associated protein 3 isoform 12

Status: VALIDATED

Source sequence(s)

AC170806

Consensus CDS

CCDS90366.1

Related

ENSMUSP00000147209.2, ENSMUST00000207533.2

Conserved Domains (5) summary

smart01051
Location:712 → 840

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:230 → 312

CAMSAP_CH; CAMSAP CH domain

cl25548
Location:471 → 539

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:494 → 592

SMC_N; RecF/RecN/SMC N terminal domain

cl28087
Location:366 → 569

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
NM_001363246.1 → NP_001350175.1 calmodulin-regulated spectrin-associated protein 3 isoform 13

Status: VALIDATED

Source sequence(s)

AC170806

Consensus CDS

CCDS90365.1

Related

ENSMUSP00000146359.2, ENSMUST00000208240.2

Conserved Domains (5) summary

smart01051
Location:708 → 836

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:225 → 307

CAMSAP_CH; CAMSAP CH domain

cl25548
Location:467 → 535

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:490 → 588

SMC_N; RecF/RecN/SMC N terminal domain

cl28087
Location:339 → 565

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
NM_001363247.1 → NP_001350176.1 calmodulin-regulated spectrin-associated protein 3 isoform 14

Status: VALIDATED

Source sequence(s)

AC170806

Conserved Domains (5) summary

smart01051
Location:707 → 835

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:225 → 307

CAMSAP_CH; CAMSAP CH domain

cl25548
Location:466 → 534

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:489 → 587

SMC_N; RecF/RecN/SMC N terminal domain

cl28087
Location:361 → 564

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
NM_001363248.1 → NP_001350177.1 calmodulin-regulated spectrin-associated protein 3 isoform 15

Status: VALIDATED

Source sequence(s)

AC170806

Consensus CDS

CCDS90367.1

Related

ENSMUSP00000146565.2, ENSMUST00000207712.2

Conserved Domains (5) summary

smart01051
Location:697 → 825

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:214 → 296

CAMSAP_CH; CAMSAP CH domain

cl25548
Location:456 → 524

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:479 → 577

SMC_N; RecF/RecN/SMC N terminal domain

cl28087
Location:328 → 554

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
NM_001363249.1 → NP_001350178.1 calmodulin-regulated spectrin-associated protein 3 isoform 16

Status: VALIDATED

Source sequence(s)

AC170806

Conserved Domains (5) summary

smart01051
Location:696 → 824

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:214 → 296

CAMSAP_CH; CAMSAP CH domain

cl25548
Location:455 → 523

DUF4670; Domain of unknown function (DUF4670)

cl25732
Location:478 → 576

SMC_N; RecF/RecN/SMC N terminal domain

cl28087
Location:350 → 553

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
NM_027171.3 → NP_081447.2 calmodulin-regulated spectrin-associated protein 3 isoform 2

See identical proteins and their annotated locations for NP_081447.2

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks two exons in the 5' coding region compared to variant 3. The encoded isoform (2) is shorter than isoform 3.

Source sequence(s)

AK081728, BC043081, CD349198, CO042496

Consensus CDS

CCDS22064.1

UniProtKB/Swiss-Prot

E9Q5B0, Q5DTW9, Q80VC9, Q8BUZ0, U5LGR7, U5LGS1, U5LGS5, U5LGT0, U5LHT8, U5LHU4, U5LHW1, U5LHW4, U5LHW9, U5LK15, U5LK19, U5LK24, U5LK70, U5LK74, U5LK79

Related

ENSMUSP00000058958.8, ENSMUST00000057028.15

Conserved Domains (3) summary

pfam08683
Location:1113 → 1231

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam11971
Location:214 → 296

CAMSAP_CH; CAMSAP CH domain

pfam17095
Location:587 → 644

CAMSAP_CC1; Spectrin-binding region of Ca2+-Calmodulin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000074.7 Reference GRCm39 C57BL/6J

Range

3637237..3659075

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006508880.2 → XP_006508943.1 calmodulin-regulated spectrin-associated protein 3 isoform X1

Conserved Domains (5) summary

PRK02224
Location:905 → 1003

PRK02224; DNA double-strand break repair Rad50 ATPase

pfam11971
Location:241 → 323

CAMSAP_CH; CAMSAP CH domain

pfam02029
Location:838 → 950

Caldesmon

pfam08683
Location:1124 → 1242

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam17095
Location:598 → 655

CAMSAP_CC1; Spectrin-binding region of Ca2+-Calmodulin
XM_036154273.1 → XP_036010166.1 calmodulin-regulated spectrin-associated protein 3 isoform X2

Conserved Domains (5) summary

PRK02224
Location:904 → 1002

PRK02224; DNA double-strand break repair Rad50 ATPase

pfam11971
Location:241 → 323

CAMSAP_CH; CAMSAP CH domain

pfam08683
Location:1123 → 1241

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam17095
Location:597 → 654

CAMSAP_CC1; Spectrin-binding region of Ca2+-Calmodulin

cl28905
Location:910 → 948

PIN_SF; PIN (PilT N terminus) domain: Superfamily
XM_030243752.1 → XP_030099612.1 calmodulin-regulated spectrin-associated protein 3 isoform X3

Conserved Domains (5) summary

PRK02224
Location:888 → 986

PRK02224; DNA double-strand break repair Rad50 ATPase

pfam11971
Location:225 → 307

CAMSAP_CH; CAMSAP CH domain

pfam02029
Location:821 → 933

Caldesmon

pfam08683
Location:1107 → 1225

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam17095
Location:581 → 638

CAMSAP_CC1; Spectrin-binding region of Ca2+-Calmodulin
XM_006508881.2 → XP_006508944.1 calmodulin-regulated spectrin-associated protein 3 isoform X4

Conserved Domains (5) summary

PRK02224
Location:789 → 887

PRK02224; DNA double-strand break repair Rad50 ATPase

pfam11971
Location:108 → 190

CAMSAP_CH; CAMSAP CH domain

pfam02029
Location:722 → 834

Caldesmon

pfam08683
Location:1008 → 1126

CAMSAP_CKK; Microtubule-binding calmodulin-regulated spectrin-associated

pfam17095
Location:482 → 539

CAMSAP_CC1; Spectrin-binding region of Ca2+-Calmodulin