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MCC MCC regulator of WNT signaling pathway [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694270, updated on 17-Aug-2024

Summary

Official Symbol
MCCprovided by VGNC
Official Full Name
MCC regulator of WNT signaling pathwayprovided by VGNC
Primary source
VGNC:VGNC:74675
See related
Ensembl:ENSMMUG00000013557
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See MCC in Genome Data Viewer
Location:
chromosome: 6
Exon count:
21
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (110536103..111010967, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (110446320..110715868, complement)

Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106998889 Neighboring gene signal recognition particle 19 Neighboring gene receptor accessory protein 5 Neighboring gene survival motor neuron protein-like Neighboring gene decapping mRNA 2 Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene U4atac minor spliceosomal RNA Neighboring gene testis specific serine kinase 1B Neighboring gene YTH N6-methyladenosine RNA binding protein C2

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
colorectal mutant cancer protein
Names
MCC, WNT signaling pathway regulator
mutated in colorectal cancers

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041759.1 Reference Mmul_10 Primary Assembly

    Range
    110536103..111010967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028849659.1XP_028705492.1  colorectal mutant cancer protein isoform X1

    UniProtKB/TrEMBL
    F7FRB5, H9F9D0
    Related
    ENSMMUP00000017830.2, ENSMMUT00000019035.4
    Conserved Domains (4) summary
    COG1196
    Location:7431006
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:198474
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam10506
    Location:587650
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
    pfam13499
    Location:3288
    EF-hand_7; EF-hand domain pair
  2. XM_002804475.3XP_002804521.1  colorectal mutant cancer protein isoform X2

    UniProtKB/TrEMBL
    A0A1D5Q4C5, F7FRA5
    Related
    ENSMMUP00000017831.1, ENSMMUT00000019036.3
    Conserved Domains (1) summary
    pfam10506
    Location:402465
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
  3. XM_015140595.2XP_014996081.1  colorectal mutant cancer protein isoform X3

    UniProtKB/TrEMBL
    A0A1D5QD96
    Conserved Domains (1) summary
    pfam10506
    Location:339402
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome