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GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 693525, updated on 17-Aug-2024

Summary

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Official Symbol
GNEprovided by VGNC
Official Full Name
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinaseprovided by VGNC
Primary source
VGNC:VGNC:103269
Locus tag
EGK_07540
See related
Ensembl:ENSMMUG00000006135
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See GNE in Genome Data Viewer
Location:
chromosome: 15
Exon count:
14
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (47873196..47934997)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (47888090..47954808)

Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 38 Neighboring gene uncharacterized LOC114672764 Neighboring gene high mobility group protein B3-like Neighboring gene U4 spliceosomal RNA Neighboring gene clathrin light chain A Neighboring gene calicin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables N-acylmannosamine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables UDP-N-acetylglucosamine 2-epimerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in UDP-N-acetylglucosamine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
Names
UDP-GlcNAc-2-epimerase/ManAc kinase
XP_014972931.1
XP_014972932.1
XP_014972933.1
XP_014972935.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041768.1 Reference Mmul_10 Primary Assembly

    Range
    47873196..47934997
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015117449.2 → XP_014972935.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X3

    UniProtKB/TrEMBL
    A0A1D5Q9K1
    Related
    ENSMMUP00000049305.2, ENSMMUT00000078114.2
    Conserved Domains (2) summary
    COG1940
    Location:404 → 708
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    cl27436
    Location:42 → 369
    Epimerase_2; UDP-N-acetylglucosamine 2-epimerase

  2. XM_015117445.2 → XP_014972931.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1

    UniProtKB/TrEMBL
    A0A1D5Q9K1, A0A663D6Y8, A0A8J8YLC7, F6PS62, G7NFA8
    Related
    ENSMMUP00000008062.4, ENSMMUT00000008576.4
    Conserved Domains (2) summary
    COG1940
    Location:440 → 744
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    cl27436
    Location:42 → 405
    Epimerase_2; UDP-N-acetylglucosamine 2-epimerase

  3. XM_015117446.1 → XP_014972932.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X2

    UniProtKB/TrEMBL
    A0A1D5Q9K1
    Conserved Domains (2) summary
    COG1940
    Location:409 → 713
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:11 → 374
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing

  4. XM_015117447.2 → XP_014972933.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X2

    UniProtKB/TrEMBL
    A0A1D5Q9K1
    Conserved Domains (2) summary
    COG1940
    Location:409 → 713
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:11 → 374
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing
Nucleotide Protein
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