Tpd52l1 TPD52 like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tpd52l1provided by RGD
Official Full Name: TPD52 like 1provided by RGD
Primary source: RGD:1594796
See related: EnsemblRapid:ENSRNOG00000021478 AllianceGenome:RGD:1594796
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable protein homodimerization activity. Predicted to be involved in G2/M transition of mitotic cell cycle and positive regulation of signal transduction. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human TPD52L1 (TPD52 like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 72.0), Heart (RPKM 66.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1p11

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (27991114..28109767)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (26172038..26290704)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (28454949..28578736)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH136796 (e-PCR)
- UniSTS:218885

RH140170 (e-PCR)
- UniSTS:222249

BF404401 (e-PCR)
- UniSTS:247088

AW524699 (e-PCR)
- UniSTS:244615

BF412420 (e-PCR)
- UniSTS:248229

AU028980 (e-PCR)
- UniSTS:111809

AU047402 (e-PCR)
- UniSTS:110545

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in G2/M transition of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in G2/M transition of mitotic cell cycle	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of JNK cascade	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of JNK cascade	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of MAP kinase activity	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of MAP kinase activity	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of apoptotic signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of apoptotic signaling pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: tumor protein D53

Names: tumor protein D52-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.