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Ppp1r27 protein phosphatase 1, regulatory subunit 27 [ Mus musculus (house mouse) ]

Gene ID: 68701, updated on 2-Nov-2024

Summary

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Official Symbol
Ppp1r27provided by MGI
Official Full Name
protein phosphatase 1, regulatory subunit 27provided by MGI
Primary source
MGI:MGI:1915951
See related
Ensembl:ENSMUSG00000025129 AllianceGenome:MGI:1915951
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
toonin; Dysfip1; 1110033I14Rik
Summary
Predicted to enable phosphatase binding activity. Orthologous to human PPP1R27 (protein phosphatase 1 regulatory subunit 27). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in mammary gland adult (RPKM 26.3), testis adult (RPKM 11.5) and 2 other tissues See more
Orthologs
human all
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Genomic context

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See Ppp1r27 in Genome Data Viewer
Location:
11 E2; 11 84.26 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (120440801..120441958, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (120549975..120551132, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene glucagon receptor Neighboring gene MAPK regulated corepressor interacting protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E8476 Neighboring gene prolyl 4-hydroxylase, beta polypeptide Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:120434472-120434581 Neighboring gene Rho GDP dissociation inhibitor alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables phosphatase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatase binding ISO
Inferred from Sequence Orthology
more info
  
enables phosphatase binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein phosphatase 1 regulatory subunit 27
Names
dysferlin-interacting protein 1
ortholog of human dysferlin interacting protein 1 (toonin) DYSFP1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026814.3 → NP_081090.1  protein phosphatase 1 regulatory subunit 27

    See identical proteins and their annotated locations for NP_081090.1

    Status: PROVISIONAL

    Source sequence(s)
    AK004064
    Consensus CDS
    CCDS36392.1
    UniProtKB/Swiss-Prot
    A2ABX5, Q9D119
    Related
    ENSMUSP00000026121.3, ENSMUST00000026121.3
    Conserved Domains (3) summary
    cd00204
    Location:38 → 147
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:38 → 127
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:63 → 94
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    120440801..120441958 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D119.1 GenPept UniProtKB/Swiss-Prot:Q9D119

Gene LinkOut

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