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Mcrip2 MAPK regulated co-repressor interacting protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685545, updated on 2-Nov-2024

Summary

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Official Symbol
Mcrip2provided by RGD
Official Full Name
MAPK regulated co-repressor interacting protein 2provided by RGD
Primary source
RGD:1592603
See related
EnsemblRapid:ENSRNOG00000020029 AllianceGenome:RGD:1592603
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam195a
Summary
Predicted to be located in cytoplasmic stress granule and nucleus. Orthologous to human MCRIP2 (MAPK regulated corepressor interacting protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 297.9), Adrenal (RPKM 274.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mcrip2 in Genome Data Viewer
Location:
10q12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15388325..15393302, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14883813..14888784, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15230801..15235740, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene rhomboid like 1 Neighboring gene ras homolog family member T2 Neighboring gene WD repeat domain 90 Neighboring gene methyltransferase like 26 Neighboring gene transfer RNA glycine (anticodon CCC) 5 Neighboring gene WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins. Bish R, et al. Biomolecules, 2015 Jul 15. PMID 26184334, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasmic stress granule ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
MAPK regulated corepressor interacting protein 2
Names
family with sequence similarity 195, member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109475.1 → NP_001102945.1  MAPK regulated corepressor interacting protein 2

    See identical proteins and their annotated locations for NP_001102945.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    A6HD70, D3ZM07
    Related
    ENSRNOP00000100984.1, ENSRNOT00000144924.1
    Conserved Domains (1) summary
    pfam14799
    Location:61 → 157
    FAM195; FAM195 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    15388325..15393302 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086832.2 → XP_038942760.1  MAPK regulated corepressor interacting protein 2 isoform X1

    Conserved Domains (1) summary
    pfam14799
    Location:61 → 137
    FAM195; FAM195 family

  2. XM_063269842.1 → XP_063125912.1  MAPK regulated corepressor interacting protein 2 isoform X3

    Related
    ENSRNOP00000027169.5, ENSRNOT00000027170.7

  3. XM_063269841.1 → XP_063125911.1  MAPK regulated corepressor interacting protein 2 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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