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Ankrd13d ankyrin repeat domain 13 family, member D [ Mus musculus (house mouse) ]

Gene ID: 68423, updated on 2-Nov-2024

Summary

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Official Symbol
Ankrd13dprovided by MGI
Official Full Name
ankyrin repeat domain 13 family, member Dprovided by MGI
Primary source
MGI:MGI:1915673
See related
Ensembl:ENSMUSG00000005986 AllianceGenome:MGI:1915673
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
0710001P18Rik
Summary
Predicted to enable ubiquitin-modified protein reader activity. Predicted to be involved in negative regulation of receptor internalization. Predicted to be located in perinuclear region of cytoplasm and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human ANKRD13D (ankyrin repeat domain 13D). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E18 (RPKM 27.3), cortex adult (RPKM 20.7) and 18 other tissues See more
Orthologs
human all
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Genomic context

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See Ankrd13d in Genome Data Viewer
Location:
19 A; 19 3.96 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (4320208..4333165, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (4270180..4284053, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1500032F14 gene Neighboring gene predicted gene, 45928 Neighboring gene polymerase (DNA-directed), delta 4 Neighboring gene STARR-positive B cell enhancer ABC_E5676 Neighboring gene microRNA 6985 Neighboring gene slingshot protein phosphatase 3 Neighboring gene STARR-positive B cell enhancer ABC_E5677 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:4294334-4294632 Neighboring gene STARR-positive B cell enhancer ABC_E7626 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:4302085-4302194 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:4302330-4302483 Neighboring gene STARR-positive B cell enhancer ABC_E9988 Neighboring gene G protein-coupled receptor kinase 2 Neighboring gene STARR-seq mESC enhancer starr_45347 Neighboring gene lysine (K)-specific demethylase 2A Neighboring gene RIKEN cDNA 9430078G10 gene Neighboring gene STARR-positive B cell enhancer ABC_E1521

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. McLelland GL, et al. Elife, 2018 Apr 20. PMID 29676259, Free PMC Article
  2. An Interaction Landscape of Ubiquitin Signaling. Zhang X, et al. Mol Cell, 2017 Mar 2. PMID 28190767
  3. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
  4. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ubiquitin-modified protein reader activity ISO
Inferred from Sequence Orthology
more info
  
enables ubiquitin-modified protein reader activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in negative regulation of receptor internalization ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of receptor internalization ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in late endosome IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
ankyrin repeat domain-containing protein 13D

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026720.2 → NP_080996.2  ankyrin repeat domain-containing protein 13D

    See identical proteins and their annotated locations for NP_080996.2

    Status: VALIDATED

    Source sequence(s)
    AK155698, BC058982
    Consensus CDS
    CCDS50351.1
    UniProtKB/Swiss-Prot
    G3X9A8, Q6PD24
    Related
    ENSMUSP00000053783.7, ENSMUST00000056888.13
    Conserved Domains (5) summary
    cd00204
    Location:9 → 97
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam11904
    Location:155 → 469
    GPCR_chapero_1; GPCR-chaperone
    pfam12796
    Location:9 → 66
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:40 → 93
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:39 → 70
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    4320208..4333165 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PD24.2 GenPept UniProtKB/Swiss-Prot:Q6PD24

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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