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Snrpg small nuclear ribonucleoprotein polypeptide G [ Rattus norvegicus (Norway rat) ]

Gene ID: 681031, updated on 28-Oct-2024

Summary

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Official Symbol
Snrpgprovided by RGD
Official Full Name
small nuclear ribonucleoprotein polypeptide Gprovided by RGD
Primary source
RGD:1584713
See related
EnsemblRapid:ENSRNOG00000016507 AllianceGenome:RGD:1584713
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables U1 snRNP binding activity. Predicted to be involved in spliceosomal snRNP assembly. Part of U1 snRNP. Orthologous to human SNRPG (small nuclear ribonucleoprotein polypeptide G). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Thymus (RPKM 904.5), Spleen (RPKM 666.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Snrpg in Genome Data Viewer
Location:
4q34
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (120369676..120377263)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (118812278..118819827)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (118167267..118174846)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350725 Neighboring gene family with sequence similarity 136, member A Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene prenylcysteine oxidase 1 Neighboring gene transfer RNA glycine (anticodon CCC) 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Low-molecular-mass secretome profiling identifies C-C motif chemokine 5 as a potential plasma biomarker and therapeutic target for nasopharyngeal carcinoma. Lin SJ, et al. J Proteomics, 2013 Dec 6. PMID 24080422
  2. Separation of nuclear protein complexes by blue native polyacrylamide gel electrophoresis. Nováková Z, et al. Electrophoresis, 2006 Apr. PMID 16502463
  3. Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis. Leung AK, et al. Nature, 2011 May 26. PMID 21516107, Free PMC Article
  4. Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. Pillai RS, et al. EMBO J, 2001 Oct 1. PMID 11574479, Free PMC Article
  5. Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition. Kondo Y, et al. Elife, 2015 Jan 2. PMID 25555158, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC188855

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables U1 snRNP binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
  
involved_in spliceosomal snRNP assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of SMN-Sm protein complex ISO
Inferred from Sequence Orthology
more info
  
part_of U1 snRNP IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U1 snRNP ISO
Inferred from Sequence Orthology
more info
  
part_of U12-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
  
part_of U2-type catalytic step 2 spliceosome ISO
Inferred from Sequence Orthology
more info
  
part_of U2-type precatalytic spliceosome ISO
Inferred from Sequence Orthology
more info
  
part_of U2-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
  
part_of U4 snRNP ISO
Inferred from Sequence Orthology
more info
  
part_of U4/U6 x U5 tri-snRNP complex ISO
Inferred from Sequence Orthology
more info
  
part_of U7 snRNP ISO
Inferred from Sequence Orthology
more info
  
part_of catalytic step 2 spliceosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
part_of methylosome ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
part_of spliceosomal complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
small nuclear ribonucleoprotein G
NP_001128557.1
XP_063142751.1
XP_063142752.1
XP_063142753.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135085.1 → NP_001128557.1  small nuclear ribonucleoprotein G

    See identical proteins and their annotated locations for NP_001128557.1

    Status: VALIDATED

    Source sequence(s)
    BC168750, BI285268
    UniProtKB/TrEMBL
    A0A8I5ZRW0, A6IAV9, B5DEP7, F7F7T6
    Related
    ENSRNOP00000022367.2, ENSRNOT00000022367.5
    Conserved Domains (1) summary
    cd01719
    Location:5 → 74
    Sm_G; Sm protein G

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    120369676..120377263
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063286683.1 → XP_063142753.1  small nuclear ribonucleoprotein G isoform X2

    UniProtKB/TrEMBL
    A6IAW0

  2. XM_063286681.1 → XP_063142751.1  small nuclear ribonucleoprotein G isoform X1

    UniProtKB/TrEMBL
    A6IAW1

  3. XM_063286682.1 → XP_063142752.1  small nuclear ribonucleoprotein G isoform X1

    UniProtKB/TrEMBL
    A6IAW1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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