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Apoc4 apolipoprotein C4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 680551, updated on 2-Nov-2024

Summary

Official Symbol
Apoc4provided by RGD
Official Full Name
apolipoprotein C4provided by RGD
Primary source
RGD:70959
See related
EnsemblRapid:ENSRNOG00000018405 AllianceGenome:RGD:70959
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Acl
Summary
Predicted to be involved in positive regulation of sequestering of triglyceride and triglyceride homeostasis. Predicted to be part of high-density lipoprotein particle and very-low-density lipoprotein particle. Orthologous to human APOC4 (apolipoprotein C4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 2950.2) See more
Orthologs
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Genomic context

See Apoc4 in Genome Data Viewer
Location:
1q21
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (88463713..88467909, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79335745..79339942, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80595339..80599525, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene CLPTM1 regulator of GABA type A receptor forward trafficking Neighboring gene uncharacterized LOC134482894 Neighboring gene apolipoprotein C2 Neighboring gene apolipoprotein C1 Neighboring gene apolipoprotein E

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of sequestering of triglyceride IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of sequestering of triglyceride ISO
Inferred from Sequence Orthology
more info
 
involved_in triglyceride homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in triglyceride homeostasis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of high-density lipoprotein particle IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of high-density lipoprotein particle ISO
Inferred from Sequence Orthology
more info
 
part_of very-low-density lipoprotein particle IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of very-low-density lipoprotein particle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
apolipoprotein C-IV
Names
ECL
apo-CIV
apoC-IV
apolipoprotein C2 linked
apolipoprotein CIV
apolipoprotein E-linked

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109419.1NP_001102889.1  apolipoprotein C-IV precursor

    See identical proteins and their annotated locations for NP_001102889.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473979
    UniProtKB/Swiss-Prot
    P55797
    UniProtKB/TrEMBL
    A6J8R1
    Related
    ENSRNOP00000024832.5, ENSRNOT00000024832.9
    Conserved Domains (1) summary
    pfam15119
    Location:28120
    APOC4; Apolipoprotein C4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    88463713..88467909 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)