Ncaph non-SMC condensin I complex, subunit H [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ncaphprovided by RGD
Official Full Name: non-SMC condensin I complex, subunit Hprovided by RGD
Primary source: RGD:1596799
See related: EnsemblRapid:ENSRNOG00000012051 AllianceGenome:RGD:1596799
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable chromatin binding activity. Predicted to be involved in nuclear chromosome segregation; positive regulation of chromosome condensation; and regulation of chromosome segregation. Predicted to act upstream of or within meiotic chromosome condensation and meiotic chromosome segregation. Predicted to be located in condensed nuclear chromosome; cytosol; and nucleoplasm. Predicted to be part of condensin complex. Predicted to be active in chromosome and nucleus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPH (non-SMC condensin I complex subunit H). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Thymus (RPKM 162.9), Spleen (RPKM 84.8) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q36

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (134825271..134852502, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (114371937..114399178, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (119583798..119611148, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH132580 (e-PCR)
- UniSTS:215863

RH125414 (e-PCR)
- UniSTS:162236

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables chromatin binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in female meiosis chromosome separation	ISO Inferred from Sequence Orthology more info
involved_in female meiotic nuclear division	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within meiotic chromosome condensation	ISO Inferred from Sequence Orthology more info
involved_in meiotic chromosome condensation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within meiotic chromosome segregation	ISO Inferred from Sequence Orthology more info
involved_in mitotic chromosome condensation	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic chromosome condensation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of chromosome condensation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of chromosome segregation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of chromosome separation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in chromosome	ISO Inferred from Sequence Orthology more info
located_in condensed nuclear chromosome	ISO Inferred from Sequence Orthology more info
part_of condensin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of condensin complex	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: condensin complex subunit 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.