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lepA translation elongation factor 4 [ Proteus mirabilis HI4320 ]

Gene ID: 6800022, updated on 6-Oct-2023

Summary

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Gene symbol
lepA
Gene description
translation elongation factor 4
Locus tag
PMI_RS09330
Gene type
protein coding
Organism
Proteus mirabilis HI4320 (strain: HI4320)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Morganellaceae; Proteus
Old locus tag
PMI1890
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Genomic context

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Sequence:
NC_010554.1 (2036340..2038136, complement)

NC_010554.1Genomic Context describing neighboring genes Neighboring gene GTPase Era Neighboring gene ribonuclease III Neighboring gene signal peptidase I Neighboring gene SoxR-reducing system protein RseC Neighboring gene sigma-E factor regulatory protein RseB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_010554.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EF4 reveals the energy barrier for tRNA back-translocation in the peptidyl transferase center. Song G, et al. RNA Biol, 2016 Oct 2. PMID 27472653, Free PMC Article
  2. The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis. Liu H, et al. Proc Natl Acad Sci U S A, 2011 Sep 27. PMID 21930951, Free PMC Article
  3. Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. Gibbs MR, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096346, Free PMC Article
  4. Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome. Kumar V, et al. J Biol Chem, 2016 Jun 17. PMID 27137929, Free PMC Article
  5. Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility. Pearson MM, et al. J Bacteriol, 2008 Jun. PMID 18375554, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
translation elongation factor 4
WP_004243894.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_010554.1 Reference assembly

    Range
    2036340..2038136 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_004243894.1 MULTISPECIES: translation elongation factor 4 [Proteus]

    See identical proteins and their annotated locations for WP_004243894.1

    UniProtKB/Swiss-Prot
    B4F049
    UniProtKB/TrEMBL
    A0A1Z1SUM1, A0A9Q4SSW6
    Conserved Domains (1) summary
    PRK05433
    Location:1 → 597
    PRK05433; GTP-binding protein LepA; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B4F049.1

Gene LinkOut

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