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zgc:136929 zgc:136929 [ Danio rerio (zebrafish) ]

Gene ID: 678649, updated on 28-Oct-2024

Summary

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Official Symbol
zgc:136929provided by ZNC
Official Full Name
zgc:136929provided by ZNC
Primary source
ZFIN:ZDB-GENE-060421-4235
See related
Ensembl:ENSDARG00000019213 AllianceGenome:ZFIN:ZDB-GENE-060421-4235
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa96d06; wu:fa96d06
Summary
Predicted to enable DNA-binding transcription factor binding activity; transcription coregulator activity; and transcription coregulator binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human CTBP1 (C-terminal binding protein 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See zgc:136929 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (21145808..21199502)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (20848544..20902254)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene si:dkey-74k8.4 Neighboring gene aldolase b, fructose-bisphosphate Neighboring gene macrophage erythroblast attacher, E3 ubiquitin ligase Neighboring gene protein phosphatase 2, regulatory subunit B, gamma b Neighboring gene si:ch211-175m2.4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC136929

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-binding transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coregulator binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
C-terminal-binding protein 1
NP_001035480.1
XP_005173191.1
XP_068069342.1
XP_068069343.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040390.1 → NP_001035480.1  C-terminal-binding protein 1

    See identical proteins and their annotated locations for NP_001035480.1

    Status: PROVISIONAL

    Source sequence(s)
    BC115334
    UniProtKB/TrEMBL
    A0A8M1N975, Q1RLQ4
    Related
    ENSDARP00000145521.1, ENSDART00000192678.1
    Conserved Domains (2) summary
    COG0111
    Location:55 → 354
    SerA; Phosphoglycerate dehydrogenase or related dehydrogenase [Coenzyme transport and metabolism, General function prediction only]
    cd05299
    Location:28 → 346
    CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    21145808..21199502
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068213241.1 → XP_068069342.1  C-terminal-binding protein 1 isoform X1

    Related
    ENSDARP00000059795.6, ENSDART00000059796.8

  2. XM_068213242.1 → XP_068069343.1  C-terminal-binding protein 1 isoform X1

    Related
    ENSDARP00000130473.1, ENSDART00000168539.2

  3. XM_005173134.5 → XP_005173191.1  C-terminal-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A2R8QPP7, A0A8M2BKF4
    Related
    ENSDARP00000155016.1, ENSDART00000187440.1
    Conserved Domains (2) summary
    COG0111
    Location:44 → 343
    SerA; Phosphoglycerate dehydrogenase or related dehydrogenase [Coenzyme transport and metabolism, General function prediction only]
    cd05299
    Location:17 → 335
    CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394903.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    2431..42137
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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