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stmn1a stathmin 1a [ Danio rerio (zebrafish) ]

Gene ID: 678630, updated on 19-May-2024

Summary

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Official Symbol
stmn1aprovided by ZNC
Official Full Name
stathmin 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031006-14
See related
Ensembl:ENSDARG00000004169 AllianceGenome:ZFIN:ZDB-GENE-031006-14
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb959; stmn1; wu:fb14e04; zgc:136942
Summary
Predicted to enable tubulin binding activity. Predicted to be involved in microtubule depolymerization; neuron projection development; and regulation of microtubule polymerization or depolymerization. Predicted to be active in cytoplasm and neuron projection. Is expressed in several structures, including digestive system; nervous system; pectoral fin bud; tail bud; and ventral mesoderm. Orthologous to human STMN1 (stathmin 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See stmn1a in Genome Data Viewer
Location:
chromosome: 19
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (17208118..17210708, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (17303757..17306346, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101884081 Neighboring gene uncharacterized LOC103909215 Neighboring gene uncharacterized LOC110438143 Neighboring gene mannosidase endo-alpha like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The Rac-GAP alpha2-Chimaerin Signals via CRMP2 and Stathmins in the Development of the Ocular Motor System. Carretero-Rodriguez L, et al. J Neurosci, 2021 Aug 4. PMID 34168008, Free PMC Article
  2. Neuropharmaceuticals in the environment: mianserin-induced neuroendocrine disruption in zebrafish (Danio rerio) using cDNA microarrays. van der Ven K, et al. Environ Toxicol Chem, 2006 Oct. PMID 17022405
  3. Dynamic microRNA-101a and Fosab expression controls zebrafish heart regeneration. Beauchemin M, et al. Development, 2015 Dec 1. PMID 26628091, Free PMC Article
  4. Dynamics of Zebrafish Heart Regeneration Using an HPLC-ESI-MS/MS Approach. Ma D, et al. J Proteome Res, 2018 Mar 2. PMID 29369637
  5. Maternal methylmercury from a wild-caught walleye diet induces developmental abnormalities in zebrafish. Liu Q, et al. Reprod Toxicol, 2016 Oct. PMID 27544571

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC136942

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in microtubule depolymerization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of microtubule polymerization or depolymerization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of microtubule polymerization or depolymerization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
stathmin 1a
Names
stathmin 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040375.1 → NP_001035465.1  stathmin 1a

    See identical proteins and their annotated locations for NP_001035465.1

    Status: PROVISIONAL

    Source sequence(s)
    BC115338
    UniProtKB/TrEMBL
    A0A8M9PNJ0, Q1RLQ1
    Related
    ENSDARP00000023151.9, ENSDART00000007906.11
    Conserved Domains (1) summary
    pfam00836
    Location:6 → 141
    Stathmin; Stathmin family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    17208118..17210708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021468136.1 → XP_021323811.1  stathmin 1a isoform X1

    UniProtKB/TrEMBL
    A0A8M9PNJ0, Q1RLQ1
    Conserved Domains (1) summary
    pfam00836
    Location:6 → 141
    Stathmin; Stathmin family
Nucleotide Protein
Heading Accession and Version

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