SNORA80E small nucleolar RNA, H/ACA box 80E [Homo sapiens (human)] - Gene

Summary

Official Symbol: SNORA80Eprovided by HGNC
Official Full Name: small nucleolar RNA, H/ACA box 80Eprovided by HGNC
Primary source: HGNC:HGNC:32635
See related: Ensembl:ENSG00000207475 AllianceGenome:HGNC:32635
Gene type: snoRNA
RefSeq status: PROVISIONAL
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: ACA42; SNORA42
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Genomic context

Location:: 1q22

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	1	NC_000001.11 (155919909..155920042, complement)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	1	NC_060925.1 (155058041..155058174, complement)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	1	NC_000001.10 (155889700..155889833, complement)

Chromosome 1 - NC_000001.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

What is the Role of SNORA42 in Carcinogenesis? A Systematic Review.
Title: What is the Role of SNORA42 in Carcinogenesis? A Systematic Review.
SNORA42 promotes oesophageal squamous cell carcinoma development through triggering the DHX9/p65 axis.
Title: SNORA42 promotes oesophageal squamous cell carcinoma development through triggering the DHX9/p65 axis.
SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis
Title: SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis.
SNORA42 expression negatively correlated with overall survival in an additional independent cohort and identified the patients with high risk for recurrence and poor prognosis in stage II CRC. Furthermore, in vitro and in vivo analyses showed that SNORA42 overexpression resulted in enhanced cell proliferation, migration, invasion, anoikis resistance and tumorigenicity.
Title: Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer.
High Small nucleolar RNA 42 is associated with lung tumorigenesis.
Title: Small nucleolar RNA 42 acts as an oncogene in lung tumorigenesis.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Other Names

ACA42 snoRNA
small nucleolar RNA, H/ACA box 42

Gene Ontology Provided by GOA

Process	Evidence Code	Pubs
involved_in RNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleolus	IEA Inferred from Electronic Annotation more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.