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Ttc33 tetratricopeptide repeat domain 33 [ Mus musculus (house mouse) ]

Gene ID: 67515, updated on 2-Nov-2024

Summary

Official Symbol
Ttc33provided by MGI
Official Full Name
tetratricopeptide repeat domain 33provided by MGI
Primary source
MGI:MGI:1914765
See related
Ensembl:ENSMUSG00000022151 AllianceGenome:MGI:1914765
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Osrf; 2410099M07Rik; 2900001O04Rik
Summary
Is expressed in central nervous system; dorsal root ganglion; and olfactory epithelium. Orthologous to human TTC33 (tetratricopeptide repeat domain 33). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in cerebellum adult (RPKM 11.6), frontal lobe adult (RPKM 10.5) and 22 other tissues See more
Orthologs
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Genomic context

See Ttc33 in Genome Data Viewer
Location:
15 A1; 15 1.99 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (5214971..5247817)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (5185490..5218336)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41256 Neighboring gene STARR-seq mESC enhancer starr_37844 Neighboring gene protein kinase, AMP-activated, alpha 1 catalytic subunit Neighboring gene predicted gene 15938 Neighboring gene heat shock protein 90, alpha (cytosolic), class A member 1 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2436 Neighboring gene prostaglandin E receptor 4 (subtype EP4) Neighboring gene STARR-seq mESC enhancer starr_37846 Neighboring gene predicted gene, 41257 Neighboring gene ribosomal protein L22 like 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
tetratricopeptide repeat protein 33
Names
TPR repeat protein 33
osmosis responsive factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355620.1NP_001342549.1  tetratricopeptide repeat protein 33

    Status: VALIDATED

    Source sequence(s)
    AC135079
    Consensus CDS
    CCDS27364.1
    UniProtKB/Swiss-Prot
    Q8VIG5, Q9D6K7
    Related
    ENSMUSP00000114033.2, ENSMUST00000118193.8
    Conserved Domains (2) summary
    COG4783
    Location:42164
    YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
    sd00006
    Location:5987
    TPR; TPR repeat [structural motif]
  2. NM_001355621.1NP_001342550.1  tetratricopeptide repeat protein 33

    Status: VALIDATED

    Source sequence(s)
    AC135079
    Consensus CDS
    CCDS27364.1
    UniProtKB/Swiss-Prot
    Q8VIG5, Q9D6K7
    Conserved Domains (2) summary
    COG4783
    Location:42164
    YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
    sd00006
    Location:5987
    TPR; TPR repeat [structural motif]
  3. NM_026213.3NP_080489.1  tetratricopeptide repeat protein 33

    See identical proteins and their annotated locations for NP_080489.1

    Status: VALIDATED

    Source sequence(s)
    AC135079
    Consensus CDS
    CCDS27364.1
    UniProtKB/Swiss-Prot
    Q8VIG5, Q9D6K7
    Related
    ENSMUSP00000022751.9, ENSMUST00000022751.15
    Conserved Domains (2) summary
    COG4783
    Location:42164
    YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
    sd00006
    Location:5987
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    5214971..5247817
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248716.1XP_030104576.1  tetratricopeptide repeat protein 33 isoform X1

    UniProtKB/Swiss-Prot
    Q8VIG5, Q9D6K7
    Conserved Domains (2) summary
    COG4783
    Location:42164
    YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
    sd00006
    Location:5987
    TPR; TPR repeat [structural motif]