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Poc5 POC5 centriolar protein [ Mus musculus (house mouse) ]

Gene ID: 67463, updated on 28-Oct-2024

Summary

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Official Symbol
Poc5provided by MGI
Official Full Name
POC5 centriolar proteinprovided by MGI
Primary source
MGI:MGI:1914713
See related
Ensembl:ENSMUSG00000021671 AllianceGenome:MGI:1914713
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1200014M14Rik
Summary
Predicted to be involved in eye photoreceptor cell development. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in centrosome and photoreceptor connecting cilium. Is expressed in central nervous system; ganglia; and sensory organ. Orthologous to human POC5 (POC5 centriolar protein). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in cerebellum adult (RPKM 5.2), whole brain E14.5 (RPKM 5.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Poc5 in Genome Data Viewer
Location:
13 D1; 13 50.56 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (96524767..96553719)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (96388259..96417211)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene synaptic vesicle glycoprotein 2c Neighboring gene STARR-seq mESC enhancer starr_35337 Neighboring gene predicted gene 29543 Neighboring gene STARR-seq mESC enhancer starr_35340 Neighboring gene STARR-seq mESC enhancer starr_35341 Neighboring gene STARR-seq mESC enhancer starr_35342 Neighboring gene STARR-seq mESC enhancer starr_35344 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:97157941-97158317 Neighboring gene SNF8, ESCRT-II complex subunit, homolog pseudogene Neighboring gene ankyrin repeat and death domain containing 1B Neighboring gene STARR-positive B cell enhancer ABC_E1884 Neighboring gene STARR-positive B cell enhancer ABC_E2418 Neighboring gene polymerase (DNA directed), kappa Neighboring gene ceramide transporter 1 Neighboring gene predicted gene, 46436

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in eye photoreceptor cell development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in centriole IEA
Inferred from Electronic Annotation
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in photoreceptor connecting cilium IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
centrosomal protein POC5
Names
POC5 centriolar protein homolog
protein of centriole 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026173.3 → NP_080449.1  centrosomal protein POC5

    See identical proteins and their annotated locations for NP_080449.1

    Status: VALIDATED

    Source sequence(s)
    AK004769, AK150656
    Consensus CDS
    CCDS26703.1
    UniProtKB/Swiss-Prot
    Q8C299, Q8CI36, Q9CZ74, Q9DBS8
    Related
    ENSMUSP00000096898.5, ENSMUST00000099295.6
    Conserved Domains (2) summary
    TIGR02168
    Location:176 → 377
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR03895
    Location:346 → 504
    protease_PatA; cyanobactin maturation protease, PatA/PatG family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    96524767..96553719
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517751.4 → XP_006517814.1  centrosomal protein POC5 isoform X1

    Conserved Domains (2) summary
    TIGR02168
    Location:150 → 351
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cl10459
    Location:320 → 478
    Peptidases_S8_S53; Peptidase domain in the S8 and S53 families

RNA

  1. XR_001780803.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DBS8.1 GenPept UniProtKB/Swiss-Prot:Q9DBS8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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