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Tmed11 transmembrane p24 trafficking protein 11 [ Mus musculus (house mouse) ]

Gene ID: 67366, updated on 18-Sep-2024

Summary

Official Symbol
Tmed11provided by MGI
Official Full Name
transmembrane p24 trafficking protein 11provided by MGI
Primary source
MGI:MGI:1914616
See related
Ensembl:ENSMUSG00000004821 AllianceGenome:MGI:1914616
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810008K16Rik
Summary
Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human TMED11P (transmembrane p24 trafficking protein 11, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Tmed11 in Genome Data Viewer
Location:
5 F; 5 53.24 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (108925101..108943229, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (108777235..108795363, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 212 Neighboring gene RIKEN cDNA 1700047L14 gene Neighboring gene 40S ribosomal protein S8 pseudogene Neighboring gene vomeronasal 2, receptor 8 Neighboring gene coiled-coil domain containing 77 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
transmembrane emp24 domain-containing protein 11
Names
GP25L
glycoprotein 25L
p24 family protein alpha-1
p24alpha1
transmembrane emp24 protein transport domain containing

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026109.2NP_080385.2  transmembrane emp24 domain-containing protein 11 precursor

    See identical proteins and their annotated locations for NP_080385.2

    Status: VALIDATED

    Source sequence(s)
    AK007381, AK019032, BY707479
    Consensus CDS
    CCDS19519.1
    UniProtKB/Swiss-Prot
    Q9D2R4
    UniProtKB/TrEMBL
    A2RTW8, Q9D941
    Related
    ENSMUSP00000004943.2, ENSMUST00000004943.2
    Conserved Domains (1) summary
    pfam01105
    Location:17209
    EMP24_GP25L; emp24/gp25L/p24 family/GOLD

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    108925101..108943229 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)