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Slc25a53 solute carrier family 25, member 53 [ Mus musculus (house mouse) ]

Gene ID: 67062, updated on 17-Aug-2024

Summary

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Official Symbol
Slc25a53provided by MGI
Official Full Name
solute carrier family 25, member 53provided by MGI
Primary source
MGI:MGI:1914312
See related
Ensembl:ENSMUSG00000044348 AllianceGenome:MGI:1914312
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mcart6; 2310046F18Rik; 2810402A17Rik
Summary
Orthologous to human SLC25A53 (solute carrier family 25 member 53). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in spleen adult (RPKM 2.0), whole brain E14.5 (RPKM 1.1) and 23 other tissues See more
Orthologs
human all
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Genomic context

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See Slc25a53 in Genome Data Viewer
Location:
X F1; X 59.1 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135881865..135939051, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136981116..137038302, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene thymosin beta 15b2 Neighboring gene thymosin beta 15b like Neighboring gene thymosin beta 15b1 Neighboring gene zinc finger, CCHC domain containing 18 Neighboring gene vacuolar ATPase assembly integral membrane protein Vma21 pseudogene Neighboring gene STARR-seq mESC enhancer starr_47980 Neighboring gene family with sequence similarity 199, X-linked Neighboring gene predicted gene, 25770

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Global expression analysis of gene regulatory pathways during endocrine pancreatic development. Gu G, et al. Development, 2004 Jan. PMID 14660441
  2. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
  3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables NAD transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
solute carrier family 25 member 53
Names
mitochondrial carrier triple repeat 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082412.2 → NP_001075881.1  solute carrier family 25 member 53 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001075881.1

    Status: PROVISIONAL

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AI448995, AK012963, AK076279, AL672008, CX240158
    Consensus CDS
    CCDS41140.1
    UniProtKB/TrEMBL
    A2AF28
    Related
    ENSMUSP00000108692.3, ENSMUST00000113069.9
    Conserved Domains (1) summary
    pfam00153
    Location:150 → 243
    Mito_carr; Mitochondrial carrier protein

  2. NM_001114179.1 → NP_001107651.1  solute carrier family 25 member 53 isoform 2

    See identical proteins and their annotated locations for NP_001107651.1

    Status: PROVISIONAL

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1.
    Source sequence(s)
    AI448995, AL672008, CX240158
    Consensus CDS
    CCDS53198.1
    UniProtKB/TrEMBL
    E9PZF7
    Related
    ENSMUSP00000132572.2, ENSMUST00000171738.2
    Conserved Domains (1) summary
    pfam00153
    Location:113 → 203
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    135881865..135939051 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247758.2 → XP_011246060.2  solute carrier family 25 member 53 isoform X1

    Conserved Domains (1) summary
    pfam00153
    Location:156 → 249
    Mito_carr; Mitochondrial carrier protein

  2. XM_006528599.5 → XP_006528662.1  solute carrier family 25 member 53 isoform X2

    See identical proteins and their annotated locations for XP_006528662.1

    UniProtKB/TrEMBL
    E9PZF7
    Conserved Domains (1) summary
    pfam00153
    Location:113 → 203
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein Strain
Heading Accession and Version

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