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lepA translation elongation factor 4 [ Streptococcus thermophilus ]

Gene ID: 66898781, updated on 10-Oct-2024

Summary

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Gene symbol
lepA
Gene description
translation elongation factor 4
Locus tag
H0506_RS04415
Gene type
protein coding
Organism
Streptococcus thermophilus (isolate: STH_CIRM_65)
Lineage
Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Old locus tag
STHERMO_0951
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Genomic context

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Location:
chromosome: STHERMO

STHERMO - NZ_LR822015.1Genomic Context describing neighboring genes Neighboring gene transporter substrate-binding domain-containing protein Neighboring gene pseudo Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_LR822015.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EF4 reveals the energy barrier for tRNA back-translocation in the peptidyl transferase center. Song G, et al. RNA Biol, 2016 Oct 2. PMID 27472653, Free PMC Article
  2. The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis. Liu H, et al. Proc Natl Acad Sci U S A, 2011 Sep 27. PMID 21930951, Free PMC Article
  3. Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. Gibbs MR, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096346, Free PMC Article
  4. Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome. Kumar V, et al. J Biol Chem, 2016 Jun 17. PMID 27137929, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
translation elongation factor 4
WP_011227164.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_LR822015.1 Reference assembly

    Range
    837532..839364
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011227164.1 translation elongation factor 4 [Streptococcus thermophilus]

    See identical proteins and their annotated locations for WP_011227164.1

    UniProtKB/Swiss-Prot
    Q03KW7, Q5M008
    UniProtKB/TrEMBL
    A0AAP2RN98
    Conserved Domains (1) summary
    PRK05433
    Location:10 → 608
    PRK05433; GTP-binding protein LepA; Provisional
Nucleotide Protein
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Gene LinkOut

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