U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pxdc1 PX domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 66895, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
Pxdc1provided by MGI
Official Full Name
PX domain containing 1provided by MGI
Primary source
MGI:MGI:1914145
See related
Ensembl:ENSMUSG00000021411 AllianceGenome:MGI:1914145
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1300014I06Rik
Summary
Predicted to enable phosphatidylinositol binding activity. Orthologous to human PXDC1 (PX domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in lung adult (RPKM 56.2), small intestine adult (RPKM 31.4) and 20 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Pxdc1 in Genome Data Viewer
Location:
13 A3.3; 13 14.16 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (34811823..34836664, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (34627840..34652681, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_34153 Neighboring gene predicted gene, 40909 Neighboring gene STARR-seq mESC enhancer starr_34154 Neighboring gene ATP synthase subunit g, mitochondrial pseudogene Neighboring gene STARR-seq mESC enhancer starr_34155 Neighboring gene STARR-seq mESC enhancer starr_34156 Neighboring gene STARR-positive B cell enhancer mm9_chr13:34735014-34735315 Neighboring gene STARR-positive B cell enhancer mm9_chr13:34735430-34735730 Neighboring gene predicted gene 15908 Neighboring gene STARR-seq mESC enhancer starr_34157 Neighboring gene family with sequence similarity 50, member B

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Hein MY, et al. Cell, 2015 Oct 22. PMID 26496610
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (3) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
PX domain-containing protein 1
Names
PX domain-containing protein C6orf145 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001382845.1 → NP_001369774.1  PX domain-containing protein 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC124687
    Conserved Domains (1) summary
    cl02563
    Location:45 → 127
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  2. NM_025831.3 → NP_080107.3  PX domain-containing protein 1 isoform 2

    See identical proteins and their annotated locations for NP_080107.3

    Status: VALIDATED

    Source sequence(s)
    AC124687, AK005003
    Consensus CDS
    CCDS36632.1
    UniProtKB/Swiss-Prot
    A0PJ93, Q8JZU6, Q9DBE6
    Related
    ENSMUSP00000051246.8, ENSMUST00000053459.15
    Conserved Domains (1) summary
    cl02563
    Location:45 → 127
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

RNA

  1. NR_168613.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124687, BC037079
    Related
    ENSMUST00000021847.15

  2. NR_168618.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124687, AK005003
    Related
    ENSMUST00000125037.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    34811823..34836664 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8JZU6.2 GenPept UniProtKB/Swiss-Prot:Q8JZU6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools