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Or1j8 olfactory receptor family 1 subfamily J member 8 [ Mus musculus (house mouse) ]

Gene ID: 666118, updated on 9-Aug-2024

Summary

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Official Symbol
Or1j8provided by MGI
Official Full Name
olfactory receptor family 1 subfamily J member 8provided by MGI
Primary source
MGI:MGI:3030169
See related
Ensembl:ENSMUSG00000113163 AllianceGenome:MGI:3030169
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr335; MOR137-2; Olfr335-ps
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the non-coding allele. [provided by RefSeq, Apr 2024]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
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Genomic context

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See Or1j8 in Genome Data Viewer
Location:
2 B; 2 24.19 cM
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (36191553..36192491)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (36301541..36302479)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene prostaglandin-endoperoxide synthase 1 Neighboring gene olfactory receptor family 1 subfamily U member 1, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_04297 Neighboring gene olfactory receptor family 1 subfamily J member 9, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_04298 Neighboring gene olfactory receptor family 1 subfamily J member 22, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The mouse olfactory receptor gene family. Godfrey PA, et al. Proc Natl Acad Sci U S A, 2004 Feb 17. PMID 14769939, Free PMC Article
  2. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  3. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  4. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  5. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor family 1 subfamily J member 8
Names
GA_x6K02T2NLDC-33001193-33002131
olfactory receptor 335, pseudogene
olfactory receptor W1UHSO2293FU.01
olfactory receptor pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001429639.1 → NP_001416568.1  olfactory receptor family 1 subfamily J member 8

    Status: VALIDATED

    Description
    Transcript Variant: This variant (coding) represents the functional allele that is not present in some strains, including the strain of the reference genome.
    Source sequence(s)
    OW971659
    UniProtKB/TrEMBL
    Q7TRY6

RNA

  1. NR_190753.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (non-coding) lacks the start codon, and represents the non-functional allele present in some strains, including the strain of the reference genome.
    Source sequence(s)
    AL929054

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    36191553..36192491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_021447.1: Suppressed sequence

    Description
    NG_021447.1: This RefSeq was removed by NCBI staff.

  2. NM_001081410.1: Suppressed sequence

    Description
    NM_001081410.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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