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Fam107b family with sequence similarity 107, member B [ Mus musculus (house mouse) ]

Gene ID: 66540, updated on 2-Nov-2024

Summary

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Official Symbol
Fam107bprovided by MGI
Official Full Name
family with sequence similarity 107, member Bprovided by MGI
Primary source
MGI:MGI:1913790
See related
Ensembl:ENSMUSG00000026655 AllianceGenome:MGI:1913790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3110001A13Rik
Summary
Acts upstream of or within sensory perception of sound. Is expressed in several structures, including cerebral cortex; choroid plexus; thymus primordium; and urinary system. Orthologous to human FAM107B (family with sequence similarity 107 member B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in thymus adult (RPKM 16.4), testis adult (RPKM 14.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Fam107b in Genome Data Viewer
Location:
2 A1; 2 2.05 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (3705049..3783179)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (3704812..3782142)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 50615 Neighboring gene STARR-positive B cell enhancer ABC_E11701 Neighboring gene STARR-positive B cell enhancer ABC_E10078 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:3575227-3575425 Neighboring gene STARR-seq mESC enhancer starr_03517 Neighboring gene STARR-seq mESC enhancer starr_03518 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:3644924-3645077 Neighboring gene STARR-positive B cell enhancer ABC_E9192 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:3673208-3673317 Neighboring gene presenilin associated, rhomboid-like pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:3717012-3717165 Neighboring gene STARR-positive B cell enhancer ABC_E5881 Neighboring gene STARR-seq mESC enhancer starr_03521 Neighboring gene STARR-seq mESC enhancer starr_03522 Neighboring gene predicted gene, 36031 Neighboring gene STARR-seq mESC enhancer starr_03523 Neighboring gene FERM domain containing 4A Neighboring gene polypyrimidine tract-binding protein 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Deciphering the spatio-temporal expression and stress regulation of Fam107B, the paralog of the resilience-promoting protein DRR1 in the mouse brain. Masana M, et al. Neuroscience, 2015 Apr 2. PMID 25637808
  2. Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. White JK, et al. Cell, 2013 Jul 18. PMID 23870131, Free PMC Article
  3. Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. Bulfone A, et al. J Neurosci, 2005 Aug 17. PMID 16107646, Free PMC Article
  4. Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. Tamplin OJ, et al. BMC Genomics, 2008 Oct 30. PMID 18973680, Free PMC Article
  5. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within sensory perception of sound IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein FAM107B
Names
novel DUF1151 domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418244.1 → NP_001405173.1  protein FAM107B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL732328, AL844530
    UniProtKB/Swiss-Prot
    Q3TGF2, Q9CR82
    Related
    ENSMUSP00000110705.3, ENSMUST00000115053.9

  2. NM_001418245.1 → NP_001405174.1  protein FAM107B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL732328, AL844530

  3. NM_001418247.1 → NP_001405176.1  protein FAM107B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL844530

  4. NM_001418248.1 → NP_001405177.1  protein FAM107B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL844530

  5. NM_001418250.1 → NP_001405179.1  protein FAM107B isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL732328, AL844530

  6. NM_001418252.1 → NP_001405181.1  protein FAM107B isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL732328, AL844530
    Related
    ENSMUSP00000110704.3, ENSMUST00000115052.9

  7. NM_001418253.1 → NP_001405182.1  protein FAM107B isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL732328, AL844530

  8. NM_025626.5 → NP_079902.1  protein FAM107B isoform 1

    See identical proteins and their annotated locations for NP_079902.1

    Status: VALIDATED

    Source sequence(s)
    AL732328, AL844530
    Consensus CDS
    CCDS15655.1
    UniProtKB/Swiss-Prot
    Q3TGF2, Q9CR82
    UniProtKB/TrEMBL
    H9H9T1
    Related
    ENSMUSP00000027965.5, ENSMUST00000027965.11
    Conserved Domains (1) summary
    pfam06625
    Location:8 → 120
    DUF1151; Protein of unknown function (DUF1151)

RNA

  1. NR_184701.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL844530

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    3705049..3783179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006497520.4 → XP_006497583.1  protein FAM107B isoform X3

    UniProtKB/TrEMBL
    H9H9T1
    Conserved Domains (1) summary
    pfam06625
    Location:37 → 148
    DUF1151; Protein of unknown function (DUF1151)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TGF2.2 GenPept UniProtKB/Swiss-Prot:Q3TGF2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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