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MCU mitochondrial calcium uniporter [ Drosophila sechellia ]

Gene ID: 6611031, updated on 22-May-2024

Summary

Gene symbol
MCU
Gene description
mitochondrial calcium uniporter
Locus tag
Dsec_GM14790
See related
EnsemblRapid:LOC6611031
Gene type
protein coding
RefSeq status
MODEL
Organism
Drosophila sechellia
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
GM14790; GM14790-PA
Orthologs
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Genomic context

See MCU in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
10
Annotation release Status Assembly Chr Location
101 current ASM438219v1 (GCF_004382195.1) 3L NC_045951.1 (6417218..6458736)

Chromosome 3L - NC_045951.1Genomic Context describing neighboring genes Neighboring gene vacuolar protein sorting 8 Neighboring gene N-deacetylase and N-sulfotransferase sfl Neighboring gene beta-Tubulin at 65B Neighboring gene protein javelin Neighboring gene serine protease nudel Neighboring gene RNA exonuclease 5 Neighboring gene zero population growth

Genomic regions, transcripts, and products

Genomic Sequence:
NC_045951.1 Chromosome 3L Reference ASM438219v1

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables uniporter activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in calcium import into the mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in mitochondrial calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of uniplex complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
calcium uniporter protein, mitochondrial
Names
Dsec\GM14790
Dsec\GM14790-PA
dsec_GLEANR_15535

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Drosophila sechellia Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM438219v1

Genomic

  1. NC_045951.1 Reference ASM438219v1

    Range
    6417218..6458736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032719742.1XP_032575633.1  calcium uniporter protein, mitochondrial isoform X1

    Related
    XP_032575633.1, XM_032719742.1
    Conserved Domains (2) summary
    pfam02037
    Location:72104
    SAP; SAP domain
    pfam04678
    Location:193395
    MCU; Mitochondrial calcium uniporter
  2. XM_032719744.1XP_032575635.1  calcium uniporter protein, mitochondrial isoform X1

    Related
    XP_032575635.1, XM_032719744.1
    Conserved Domains (2) summary
    pfam02037
    Location:72104
    SAP; SAP domain
    pfam04678
    Location:193395
    MCU; Mitochondrial calcium uniporter
  3. XM_032719746.1XP_032575637.1  calcium uniporter protein, mitochondrial isoform X2

    Related
    XP_032575637.1, XM_032719746.1
    Conserved Domains (2) summary
    pfam02037
    Location:72104
    SAP; SAP domain
    pfam04678
    Location:192394
    MCU; Mitochondrial calcium uniporter
  4. XM_032719741.1XP_032575632.1  calcium uniporter protein, mitochondrial isoform X1

    Related
    XP_032575632.1, XM_032719741.1
    Conserved Domains (2) summary
    pfam02037
    Location:72104
    SAP; SAP domain
    pfam04678
    Location:193395
    MCU; Mitochondrial calcium uniporter
  5. XM_032719743.1XP_032575634.1  calcium uniporter protein, mitochondrial isoform X1

    Related
    XP_032575634.1, XM_032719743.1
    Conserved Domains (2) summary
    pfam02037
    Location:72104
    SAP; SAP domain
    pfam04678
    Location:193395
    MCU; Mitochondrial calcium uniporter
  6. XM_032719747.1XP_032575638.1  calcium uniporter protein, mitochondrial isoform X4

    Related
    XP_032575638.1, XM_032719747.1
    Conserved Domains (1) summary
    pfam04678
    Location:115317
    MCU; Mitochondrial calcium uniporter
  7. XM_002035552.2XP_002035588.1  calcium uniporter protein, mitochondrial isoform X3

    See identical proteins and their annotated locations for XP_002035588.1

    UniProtKB/TrEMBL
    B4HUV3
    Related
    XP_002035588.1, XM_002035552.2
    Conserved Domains (1) summary
    pfam04678
    Location:116318
    MCU; Mitochondrial calcium uniporter
  8. XM_032719745.1XP_032575636.1  calcium uniporter protein, mitochondrial isoform X1

    Related
    XP_032575636.1, XM_032719745.1
    Conserved Domains (2) summary
    pfam02037
    Location:72104
    SAP; SAP domain
    pfam04678
    Location:193395
    MCU; Mitochondrial calcium uniporter