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Rmnd1 required for meiotic nuclear division 1 homolog [ Mus musculus (house mouse) ]

Gene ID: 66084, updated on 2-Nov-2024

Summary

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Official Symbol
Rmnd1provided by MGI
Official Full Name
required for meiotic nuclear division 1 homologprovided by MGI
Primary source
MGI:MGI:1913334
See related
Ensembl:ENSMUSG00000019763 AllianceGenome:MGI:1913334
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
0610042C05Rik
Summary
Predicted to be involved in positive regulation of mitochondrial translation. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 11. Orthologous to human RMND1 (required for meiotic nuclear division 1 homolog). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis adult (RPKM 26.5), kidney adult (RPKM 13.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Rmnd1 in Genome Data Viewer
Location:
10 A1; 10 2.06 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (4353168..4382583, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (4403169..4432405, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_25640 Neighboring gene A kinase anchor protein 12 Neighboring gene predicted gene, 40592 Neighboring gene STARR-seq mESC enhancer starr_25637 Neighboring gene STARR-positive B cell enhancer ABC_E11428 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5999414-5999597 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5988889-5989072 Neighboring gene STARR-seq mESC enhancer starr_25630 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5958087-5958270 Neighboring gene zinc finger and BTB domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E2315 Neighboring gene acidic residue methyltransferase 1 Neighboring gene STARR-seq mESC enhancer starr_25628 Neighboring gene coiled-coil domain containing 170 Neighboring gene predicted gene, 22739 Neighboring gene STARR-seq mESC enhancer starr_25624 Neighboring gene glutathione S-transferase, pi 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Kalsotra A, et al. Proc Natl Acad Sci U S A, 2008 Dec 23. PMID 19075228, Free PMC Article
  2. The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes. Liu F, et al. Mol Cell Proteomics, 2018 Feb. PMID 29222160, Free PMC Article
  3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in positive regulation of mitochondrial translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of mitochondrial translation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of mitochondrial translation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
required for meiotic nuclear division protein 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358796.2 → NP_001345725.1  required for meiotic nuclear division protein 1 homolog isoform a

    Status: VALIDATED

    Source sequence(s)
    AC133902
    Consensus CDS
    CCDS56675.1
    UniProtKB/Swiss-Prot
    Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
    Conserved Domains (1) summary
    pfam02582
    Location:227 → 404
    DUF155; Uncharacterized ACR, YagE family COG1723

  2. NM_001429326.1 → NP_001416255.1  required for meiotic nuclear division protein 1 homolog isoform a

    Status: VALIDATED

    Source sequence(s)
    AC133902
    UniProtKB/Swiss-Prot
    Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0

  3. NM_001429327.1 → NP_001416256.1  required for meiotic nuclear division protein 1 homolog isoform a

    Status: VALIDATED

    Source sequence(s)
    AC133902
    UniProtKB/Swiss-Prot
    Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0

  4. NM_001429328.1 → NP_001416257.1  required for meiotic nuclear division protein 1 homolog isoform a

    Status: VALIDATED

    Source sequence(s)
    AC133902
    UniProtKB/Swiss-Prot
    Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0

  5. NM_001429329.1 → NP_001416258.1  required for meiotic nuclear division protein 1 homolog isoform a

    Status: VALIDATED

    Source sequence(s)
    AC133902
    UniProtKB/Swiss-Prot
    Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0

  6. NM_001429330.1 → NP_001416259.1  required for meiotic nuclear division protein 1 homolog isoform b

    Status: VALIDATED

    Source sequence(s)
    AC133902

  7. NM_001429331.1 → NP_001416260.1  required for meiotic nuclear division protein 1 homolog isoform c

    Status: VALIDATED

    Source sequence(s)
    AC133902

  8. NM_001429332.1 → NP_001416261.1  required for meiotic nuclear division protein 1 homolog isoform c

    Status: VALIDATED

    Source sequence(s)
    AC133902

  9. NM_025343.7 → NP_079619.4  required for meiotic nuclear division protein 1 homolog isoform a

    See identical proteins and their annotated locations for NP_079619.4

    Status: VALIDATED

    Source sequence(s)
    AC133902
    Consensus CDS
    CCDS56675.1
    UniProtKB/Swiss-Prot
    Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
    Related
    ENSMUSP00000043355.5, ENSMUST00000042251.11
    Conserved Domains (1) summary
    pfam02582
    Location:227 → 404
    DUF155; Uncharacterized ACR, YagE family COG1723

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    4353168..4382583 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512478.5 → XP_006512541.1  required for meiotic nuclear division protein 1 homolog isoform X1

    Conserved Domains (1) summary
    pfam02582
    Location:227 → 404
    DUF155; Uncharacterized ACR, YagE family COG1723

  2. XM_036155948.1 → XP_036011841.1  required for meiotic nuclear division protein 1 homolog isoform X3

    Conserved Domains (1) summary
    pfam02582
    Location:15 → 192
    DUF155; Uncharacterized ACR, YagE family COG1723

  3. XM_036155947.1 → XP_036011840.1  required for meiotic nuclear division protein 1 homolog isoform X3

    Conserved Domains (1) summary
    pfam02582
    Location:15 → 192
    DUF155; Uncharacterized ACR, YagE family COG1723

  4. XM_017314053.3 → XP_017169542.1  required for meiotic nuclear division protein 1 homolog isoform X1

    Conserved Domains (1) summary
    pfam02582
    Location:227 → 404
    DUF155; Uncharacterized ACR, YagE family COG1723

  5. XM_036155945.1 → XP_036011838.1  required for meiotic nuclear division protein 1 homolog isoform X1

    UniProtKB/Swiss-Prot
    Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
    Conserved Domains (1) summary
    pfam02582
    Location:227 → 404
    DUF155; Uncharacterized ACR, YagE family COG1723

  6. XM_006512477.5 → XP_006512540.1  required for meiotic nuclear division protein 1 homolog isoform X1

    Conserved Domains (1) summary
    pfam02582
    Location:227 → 404
    DUF155; Uncharacterized ACR, YagE family COG1723

  7. XM_036155944.1 → XP_036011837.1  required for meiotic nuclear division protein 1 homolog isoform X1

    UniProtKB/Swiss-Prot
    Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
    Conserved Domains (1) summary
    pfam02582
    Location:227 → 404
    DUF155; Uncharacterized ACR, YagE family COG1723

  8. XM_036155952.1 → XP_036011845.1  required for meiotic nuclear division protein 1 homolog isoform X4

    Conserved Domains (1) summary
    pfam02582
    Location:6 → 160
    DUF155; Uncharacterized ACR, YagE family COG1723

  9. XM_036155951.1 → XP_036011844.1  required for meiotic nuclear division protein 1 homolog isoform X4

    Conserved Domains (1) summary
    pfam02582
    Location:6 → 160
    DUF155; Uncharacterized ACR, YagE family COG1723

  10. XM_036155950.1 → XP_036011843.1  required for meiotic nuclear division protein 1 homolog isoform X4

    Conserved Domains (1) summary
    pfam02582
    Location:6 → 160
    DUF155; Uncharacterized ACR, YagE family COG1723

  11. XM_036155949.1 → XP_036011842.1  required for meiotic nuclear division protein 1 homolog isoform X4

    Conserved Domains (1) summary
    pfam02582
    Location:6 → 160
    DUF155; Uncharacterized ACR, YagE family COG1723

  12. XM_017314054.3 → XP_017169543.1  required for meiotic nuclear division protein 1 homolog isoform X1

    Conserved Domains (1) summary
    pfam02582
    Location:227 → 404
    DUF155; Uncharacterized ACR, YagE family COG1723

  13. XM_036155943.1 → XP_036011836.1  required for meiotic nuclear division protein 1 homolog isoform X1

    UniProtKB/Swiss-Prot
    Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
    Conserved Domains (1) summary
    pfam02582
    Location:227 → 404
    DUF155; Uncharacterized ACR, YagE family COG1723

  14. XM_036155946.1 → XP_036011839.1  required for meiotic nuclear division protein 1 homolog isoform X2

RNA

  1. XR_004936244.1 RNA Sequence

  2. XR_004936243.1 RNA Sequence

  3. XR_004936245.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CI78.1 GenPept UniProtKB/Swiss-Prot:Q8CI78

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