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Tmem42 transmembrane protein 42 [ Mus musculus (house mouse) ]

Gene ID: 66079, updated on 2-Nov-2024

Summary

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Official Symbol
Tmem42provided by MGI
Official Full Name
transmembrane protein 42provided by MGI
Primary source
MGI:MGI:1277176
See related
Ensembl:ENSMUSG00000066233 AllianceGenome:MGI:1277176
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D9Ertd662e; 0610027O18Rik; 4933429E06Rik
Summary
Predicted to be located in membrane. Orthologous to human TMEM42 (transmembrane protein 42). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in adrenal adult (RPKM 30.6), lung adult (RPKM 16.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Tmem42 in Genome Data Viewer
Location:
9 F4; 9 73.52 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (122850072..122852556)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (123021007..123023491)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1110059G10 gene Neighboring gene STARR-seq mESC enhancer starr_25555 Neighboring gene STARR-seq mESC enhancer starr_25556 Neighboring gene kinesin family member 15 Neighboring gene predicted gene, 35691 Neighboring gene predicted gene 9856 Neighboring gene transglutaminase 4 (prostate) Neighboring gene zinc finger, DHHC domain containing 3 Neighboring gene exosome component 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
  2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC29956

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 42

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164823.1 → NP_001158295.1  transmembrane protein 42 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to variant 1.
    Source sequence(s)
    AA939506, AC133650, AK012820, BX515032
    Consensus CDS
    CCDS90690.1
    UniProtKB/TrEMBL
    A0A1L1SRQ7
    Related
    ENSMUSP00000149571.2, ENSMUST00000213514.2

  2. NM_025339.4 → NP_079615.1  transmembrane protein 42 isoform 1

    See identical proteins and their annotated locations for NP_079615.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC133650, AK012820, BX515032
    Consensus CDS
    CCDS23652.1
    UniProtKB/Swiss-Prot
    Q9CR22
    Related
    ENSMUSP00000081784.6, ENSMUST00000084733.7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    122850072..122852556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512206.4 → XP_006512269.1  transmembrane protein 42 isoform X1

    See identical proteins and their annotated locations for XP_006512269.1

    UniProtKB/Swiss-Prot
    Q9CR22

  2. XM_006512205.3 → XP_006512268.1  transmembrane protein 42 isoform X1

    See identical proteins and their annotated locations for XP_006512268.1

    UniProtKB/Swiss-Prot
    Q9CR22
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CR22.1 GenPept UniProtKB/Swiss-Prot:Q9CR22

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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