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GOLGA8K golgin A8 family member K [ Homo sapiens (human) ]

Gene ID: 653125, updated on 23-Nov-2023

Summary

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Official Symbol
GOLGA8Kprovided by HGNC
Official Full Name
golgin A8 family member Kprovided by HGNC
Primary source
HGNC:HGNC:38652
See related
Ensembl:ENSG00000249931 AllianceGenome:HGNC:38652
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in Golgi organization. Predicted to be active in Golgi cis cisterna; Golgi cisterna membrane; and cis-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in thyroid (RPKM 19.0), testis (RPKM 15.0) and 25 other tissues See more
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Genomic context

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Location:
15q13.3
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (32389599..32403292, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (30186123..30199816, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (32681800..32695493, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112268159 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:32679479-32679978 Neighboring gene uncharacterized LOC107987221 Neighboring gene dynamin 1 pseudogene 31 Neighboring gene uncharacterized LOC124903457 Neighboring gene RNA, 7SL, cytoplasmic 185, pseudogene Neighboring gene 15q13.2-13.3 gamma inversion distal recombination region Neighboring gene ULK4 pseudogene 1 Neighboring gene U8 small nucleolar RNA Neighboring gene dynamin 1 pseudogene 32

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. Zody MC, et al. Nature, 2006 Mar 30. PMID 16572171
  2. Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer. Vichas A, et al. Nat Commun, 2021 Aug 9. PMID 34373451, Free PMC Article
  3. A reference map of the human binary protein interactome. Luck K, et al. Nature, 2020 Apr. PMID 32296183, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Potential readthrough

Included gene: ULK4P1

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi cis cisterna IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in Golgi cisterna membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cis-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
golgin subfamily A member 8K
Names
Golgin subfamily A member 8K

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001282493.2 → NP_001269422.1  golgin subfamily A member 8K

    Status: VALIDATED

    Source sequence(s)
    AC139426
    Consensus CDS
    CCDS61577.1
    UniProtKB/Swiss-Prot
    D6RF30
    UniProtKB/TrEMBL
    A0A1B0GVY7
    Related
    ENSP00000426691.2, ENST00000512626.3
    Conserved Domains (2) summary
    pfam15070
    Location:226 → 620
    GOLGA2L5; Putative golgin subfamily A member 2-like protein 5
    cl19219
    Location:175 → 291
    DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    32389599..32403292 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_012132920.1 Reference GRCh38.p14 PATCHES

    Range
    122720..136427
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    30186123..30199816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D6RF30.2 GenPept UniProtKB/Swiss-Prot:D6RF30

Gene LinkOut

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