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GOLGA8S golgin A8 family member S [ Homo sapiens (human) ]

Gene ID: 653061, updated on 5-Mar-2024

Summary

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Official Symbol
GOLGA8Sprovided by HGNC
Official Full Name
golgin A8 family member Sprovided by HGNC
Primary source
HGNC:HGNC:44409
See related
Ensembl:ENSG00000261739 AllianceGenome:HGNC:44409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in Golgi organization. Predicted to be active in Golgi cis cisterna; Golgi cisterna membrane; and cis-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 16.5), thyroid (RPKM 6.9) and 14 other tissues See more
Orthologs
all
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Genomic context

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See GOLGA8S in Genome Data Viewer
Location:
15q11.2
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (23354748..23368489)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (21091026..21104791)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (23599895..23613636)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene golgin A6 family like 26 Neighboring gene uncharacterized LOC105376698 Neighboring gene uncharacterized LOC105370726 Neighboring gene RNA, 7SL, cytoplasmic 536, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:23618137-23618636 Neighboring gene uncharacterized LOC124903446 Neighboring gene uncharacterized LOC105370728

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. Zody MC, et al. Nature, 2006 Mar 30. PMID 16572171
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi cis cisterna IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in Golgi cisterna membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cis-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
golgin subfamily A member 8S

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355465.2 → NP_001342394.1  golgin subfamily A member 8S isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC100756
    Conserved Domains (1) summary
    pfam15070
    Location:13 → 402
    GOLGA2L5; Putative golgin subfamily A member 2-like protein 5

  2. NM_001395373.1 → NP_001382302.1  golgin subfamily A member 8S isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC100756
    Consensus CDS
    CCDS91964.1
    UniProtKB/Swiss-Prot
    H3BPF8
    Related
    ENSP00000455298.2, ENST00000562295.3
    Conserved Domains (1) summary
    COG1196
    Location:109 → 404
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    23354748..23368489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_021160017.1 Reference GRCh38.p14 PATCHES

    Range
    4303955..4317696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    21091026..21104791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054378653.1 → XP_054234628.1  golgin subfamily A member 8S isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_038843.1: Suppressed sequence

    Description
    NR_038843.1: This RefSeq was removed because it is now thought that this locus encodes a protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
H3BPF8.2 GenPept UniProtKB/Swiss-Prot:H3BPF8

Gene LinkOut

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