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MPPE1 metallophosphoesterase 1 [ Homo sapiens (human) ]

Gene ID: 65258, updated on 3-Apr-2024

Summary

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Official Symbol
MPPE1provided by HGNC
Official Full Name
metallophosphoesterase 1provided by HGNC
Primary source
HGNC:HGNC:15988
See related
Ensembl:ENSG00000154889 MIM:611900; AllianceGenome:HGNC:15988
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Cdc1; PGAP5
Summary
Predicted to enable GPI anchor binding activity; GPI-mannose ethanolamine phosphate phosphodiesterase activity; and manganese ion binding activity. Involved in GPI anchor biosynthetic process. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thyroid (RPKM 13.2), prostate (RPKM 8.5) and 25 other tissues See more
Orthologs
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Genomic context

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Location:
18p11.21
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (11882622..11908317, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (12045331..12071022, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (11882621..11908316, complement)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene G protein subunit alpha L Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr18:11856862-11858061 Neighboring gene uncharacterized LOC124904251 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:11861344-11862250 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:11875590-11875801 Neighboring gene uncharacterized LOC124904252 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9301 Neighboring gene uncharacterized LOC101927511 Neighboring gene CRISPRi-validated cis-regulatory element chr18.397 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:11951641-11952330 Neighboring gene Sharpr-MPRA regulatory region 7933 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13098 Neighboring gene inositol monophosphatase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Metallophosphoesterase 1, a novel candidate gene in hepatocellular carcinoma malignancy and recurrence. Chen X, et al. Cancer Biol Ther, 2020 Nov 1. PMID 33054568, Free PMC Article
  2. Association between polymorphisms in the metallophosphoesterase (MPPE1) gene and bipolar disorder. Lohoff FW, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Apr 5. PMID 19859903, Free PMC Article
  3. cDNA cloning, genomic organization and expression of the novel human metallophosphoesterase gene MPPE1 on chromosome 18p11.2. Vuoristo JT, et al. Cytogenet Cell Genet, 2001. PMID 11978971
  4. GPI glycan remodeling by PGAP5 regulates transport of GPI-anchored proteins from the ER to the Golgi. Fujita M, et al. Cell, 2009 Oct 16. PMID 19837036
  5. Identification of a Golgi GPI-N-acetylgalactosamine transferase with tandem transmembrane regions in the catalytic domain. Hirata T, et al. Nat Commun, 2018 Jan 26. PMID 29374258, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Metallophosphoesterase 1, a novel candidate gene in hepatocellular carcinoma malignancy and recurrence.
    Title: Metallophosphoesterase 1, a novel candidate gene in hepatocellular carcinoma malignancy and recurrence.
  2. These results provide evidence of an association between a polymorphism in the MPPE1 gene and bipolar disorder.
    Title: Association between polymorphisms in the metallophosphoesterase (MPPE1) gene and bipolar disorder.
  3. Data demonstrate that glycosylphosphatidylinositol(GPI) glycan acts as an endoplasmic reticulum-exit signal and suggest that glycan remodeling mediated by PGAP5 regulates GPI-anchored proteins transport in the early secretory pathway.
    Title: GPI glycan remodeling by PGAP5 regulates transport of GPI-anchored proteins from the ER to the Golgi.
  4. Observational study of gene-disease association. (HuGE Navigator)
    Title: Association between polymorphisms in the metallophosphoesterase (MPPE1) gene and bipolar disorder.
  5. cDNA cloning, genomic organization and expression of the novel human metallophosphoesterase gene MPPE1 on chromosome 18p11.2
    Title: cDNA cloning, genomic organization and expression of the novel human metallophosphoesterase gene MPPE1 on chromosome 18p11.2.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GPI anchor binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables GPI-mannose ethanolamine phosphate phosphodiesterase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables manganese ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in GPI anchor biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
  
located_in cis-Golgi network ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endoplasmic reticulum exit site ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endoplasmic reticulum-Golgi intermediate compartment ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endoplasmic reticulum-Golgi intermediate compartment membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  

General protein information

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Preferred Names
metallophosphoesterase 1
Names
metallo phosphoesterase
post-GPI attachment to proteins 5
post-GPI attachment to proteins factor 5
NP_001229833.1
NP_001306083.1
NP_001317492.1
NP_075563.3
XP_006722403.1
XP_006722404.1
XP_006722405.1
XP_006722406.1
XP_006722408.1
XP_006722409.1
XP_006722411.1
XP_011524033.1
XP_011524034.1
XP_016881411.1
XP_016881412.1
XP_016881413.1
XP_016881414.1
XP_016881416.1
XP_016881417.1
XP_016881418.1
XP_016881419.1
XP_016881420.1
XP_047293699.1
XP_047293700.1
XP_047293701.1
XP_047293702.1
XP_047293703.1
XP_047293704.1
XP_047293705.1
XP_047293706.1
XP_047293707.1
XP_047293708.1
XP_047293709.1
XP_047293710.1
XP_047293711.1
XP_047293712.1
XP_054174962.1
XP_054174963.1
XP_054174964.1
XP_054174965.1
XP_054174966.1
XP_054174967.1
XP_054174968.1
XP_054174969.1
XP_054174970.1
XP_054174971.1
XP_054174972.1
XP_054174973.1
XP_054174974.1
XP_054174975.1
XP_054174976.1
XP_054174977.1
XP_054174978.1
XP_054174979.1
XP_054174980.1
XP_054174981.1
XP_054174982.1
XP_054174983.1
XP_054174984.1
XP_054174985.1
XP_054174986.1
XP_054174987.1
XP_054174988.1
XP_054174989.1
XP_054174990.1
XP_054174991.1
XP_054174992.1
XP_054174993.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242904.2 → NP_001229833.1  metallophosphoesterase 1 isoform 2

    See identical proteins and their annotated locations for NP_001229833.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5'UTR and lacks two consecutive exons in the central coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Both variants 2 and 6 encode the same isoform.
    Source sequence(s)
    AL833636, AP001269, AW663162, BC002877, CR738004, DB035278
    Consensus CDS
    CCDS56054.1
    UniProtKB/Swiss-Prot
    Q53F39
    Related
    ENSP00000311200.9, ENST00000309976.13
    Conserved Domains (1) summary
    cd08165
    Location:73 → 266
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain

  2. NM_001319154.2 → NP_001306083.1  metallophosphoesterase 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks two consecutive exons in the central coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Both variants 2 and 6 encode the same isoform.
    Source sequence(s)
    AL536593, AL833636, AP001269
    Consensus CDS
    CCDS56054.1
    UniProtKB/Swiss-Prot
    Q53F39
    Related
    ENSP00000327257.6, ENST00000317235.11
    Conserved Domains (1) summary
    cd08165
    Location:73 → 266
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain

  3. NM_001330563.2 → NP_001317492.1  metallophosphoesterase 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL833636, AP001269
    Consensus CDS
    CCDS82242.1
    UniProtKB/TrEMBL
    A0A0A0MR93
    Related
    ENSP00000339423.7, ENST00000344987.11
    Conserved Domains (2) summary
    cd08165
    Location:73 → 307
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 283
    Metallophos; Calcineurin-like phosphoesterase

  4. NM_023075.6 → NP_075563.3  metallophosphoesterase 1 isoform 1

    See identical proteins and their annotated locations for NP_075563.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AF363484, AL833636, AP001269, AW663162, BC002877, DB035278
    Consensus CDS
    CCDS11853.1
    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4
    Related
    ENSP00000465894.1, ENST00000588072.6
    Conserved Domains (2) summary
    cd08165
    Location:73 → 329
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 305
    Metallophos; Calcineurin-like phosphoesterase

RNA

  1. NR_040241.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) includes an alternate penultimate exon. This results in a frameshift and premature stop codon which renders the transcript a candidate for nonsense-mediated decay (NMD).
    Source sequence(s)
    AF289560, AL833636, AP001269, AW663162, BC073994

  2. NR_040242.4 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) includes 2 alternate exons and represents use of an alternate splice acceptor site, compared to variant 1. These differences result in a frameshift and premature stop codon which renders the transcript a candidate for nonsense-mediated decay (NMD).
    Source sequence(s)
    AK021647, AK054639, AL833636, AP001269, AW663162, BC073994, DB035278

  3. NR_040243.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) includes an alternate penultimate exon compared to variant 1. This results in a frameshift and premature stop codon which renders the transcript a candidate for nonsense-mediated decay (NMD).
    Source sequence(s)
    AL833636, AP001269, AW663162, BC002877, BC073994, CR738004, DB035278

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    11882622..11908317 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017025929.3 → XP_016881418.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93
    Conserved Domains (2) summary
    cd08165
    Location:73 → 307
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 283
    Metallophos; Calcineurin-like phosphoesterase

  2. XM_006722346.4 → XP_006722409.1  metallophosphoesterase 1 isoform X2

    See identical proteins and their annotated locations for XP_006722409.1

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4
    Conserved Domains (2) summary
    cd08165
    Location:73 → 329
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 305
    Metallophos; Calcineurin-like phosphoesterase

  3. XM_006722345.5 → XP_006722408.1  metallophosphoesterase 1 isoform X1

    See identical proteins and their annotated locations for XP_006722408.1

    Conserved Domains (2) summary
    cd08165
    Location:73 → 330
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 306
    Metallophos; Calcineurin-like phosphoesterase

  4. XM_006722340.4 → XP_006722403.1  metallophosphoesterase 1 isoform X1

    See identical proteins and their annotated locations for XP_006722403.1

    Conserved Domains (2) summary
    cd08165
    Location:73 → 330
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 306
    Metallophos; Calcineurin-like phosphoesterase

  5. XM_017025927.3 → XP_016881416.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93
    Conserved Domains (2) summary
    cd08165
    Location:73 → 307
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 283
    Metallophos; Calcineurin-like phosphoesterase

  6. XM_017025924.3 → XP_016881413.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4
    Conserved Domains (2) summary
    cd08165
    Location:73 → 329
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 305
    Metallophos; Calcineurin-like phosphoesterase

  7. XM_006722342.5 → XP_006722405.1  metallophosphoesterase 1 isoform X1

    See identical proteins and their annotated locations for XP_006722405.1

    Conserved Domains (2) summary
    cd08165
    Location:73 → 330
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 306
    Metallophos; Calcineurin-like phosphoesterase

  8. XM_017025928.2 → XP_016881417.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93
    Conserved Domains (2) summary
    cd08165
    Location:73 → 307
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 283
    Metallophos; Calcineurin-like phosphoesterase

  9. XM_017025925.2 → XP_016881414.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4
    Conserved Domains (2) summary
    cd08165
    Location:73 → 329
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 305
    Metallophos; Calcineurin-like phosphoesterase

  10. XM_006722343.4 → XP_006722406.1  metallophosphoesterase 1 isoform X1

    See identical proteins and their annotated locations for XP_006722406.1

    Conserved Domains (2) summary
    cd08165
    Location:73 → 330
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 306
    Metallophos; Calcineurin-like phosphoesterase

  11. XM_047437753.1 → XP_047293709.1  metallophosphoesterase 1 isoform X6

  12. XM_047437748.1 → XP_047293704.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93

  13. XM_017025922.3 → XP_016881411.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4
    Conserved Domains (2) summary
    cd08165
    Location:73 → 329
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 305
    Metallophos; Calcineurin-like phosphoesterase

  14. XM_006722341.5 → XP_006722404.1  metallophosphoesterase 1 isoform X1

    See identical proteins and their annotated locations for XP_006722404.1

    Conserved Domains (2) summary
    cd08165
    Location:73 → 330
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 306
    Metallophos; Calcineurin-like phosphoesterase

  15. XM_047437746.1 → XP_047293702.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4

  16. XM_047437745.1 → XP_047293701.1  metallophosphoesterase 1 isoform X1

  17. XM_047437754.1 → XP_047293710.1  metallophosphoesterase 1 isoform X6

  18. XM_017025923.3 → XP_016881412.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4
    Conserved Domains (2) summary
    cd08165
    Location:73 → 329
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 305
    Metallophos; Calcineurin-like phosphoesterase

  19. XM_011525731.4 → XP_011524033.1  metallophosphoesterase 1 isoform X1

    See identical proteins and their annotated locations for XP_011524033.1

    Conserved Domains (2) summary
    cd08165
    Location:73 → 330
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 306
    Metallophos; Calcineurin-like phosphoesterase

  20. XM_047437744.1 → XP_047293700.1  metallophosphoesterase 1 isoform X1

  21. XM_047437749.1 → XP_047293705.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93

  22. XM_047437747.1 → XP_047293703.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4

  23. XM_047437743.1 → XP_047293699.1  metallophosphoesterase 1 isoform X1

  24. XM_017025930.3 → XP_016881419.1  metallophosphoesterase 1 isoform X5

    UniProtKB/TrEMBL
    K7ES91
    Related
    ENSP00000468606.1, ENST00000592977.5
    Conserved Domains (2) summary
    cd08165
    Location:73 → 329
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 305
    Metallophos; Calcineurin-like phosphoesterase

  25. XM_047437750.1 → XP_047293706.1  metallophosphoesterase 1 isoform X5

    Related
    ENSP00000433950.1, ENST00000496196.5

  26. XM_011525732.3 → XP_011524034.1  metallophosphoesterase 1 isoform X4

    UniProtKB/TrEMBL
    K7ES91
    Conserved Domains (2) summary
    cd08165
    Location:73 → 330
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 306
    Metallophos; Calcineurin-like phosphoesterase

  27. XM_047437752.1 → XP_047293708.1  metallophosphoesterase 1 isoform X5

  28. XM_047437756.1 → XP_047293712.1  metallophosphoesterase 1 isoform X10

  29. XM_047437755.1 → XP_047293711.1  metallophosphoesterase 1 isoform X7

  30. XM_047437751.1 → XP_047293707.1  metallophosphoesterase 1 isoform X5

  31. XM_006722348.3 → XP_006722411.1  metallophosphoesterase 1 isoform X9

    UniProtKB/TrEMBL
    K7ES91
    Conserved Domains (2) summary
    cd08165
    Location:73 → 178
    MPP_MPPE1; human MPPE1 and related proteins, metallophosphatase domain
    pfam00149
    Location:70 → 194
    Metallophos; Calcineurin-like phosphoesterase

  32. XM_017025931.2 → XP_016881420.1  metallophosphoesterase 1 isoform X8

    UniProtKB/TrEMBL
    K7ES91
    Related
    ENST00000589731.5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    12045331..12071022 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054319007.1 → XP_054174982.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93

  2. XM_054319002.1 → XP_054174977.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4

  3. XM_054318992.1 → XP_054174967.1  metallophosphoesterase 1 isoform X1

  4. XM_054318987.1 → XP_054174962.1  metallophosphoesterase 1 isoform X1

  5. XM_054319004.1 → XP_054174979.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93

  6. XM_054318997.1 → XP_054174972.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4

  7. XM_054318989.1 → XP_054174964.1  metallophosphoesterase 1 isoform X1

  8. XM_054319006.1 → XP_054174981.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93

  9. XM_054319001.1 → XP_054174976.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4

  10. XM_054318991.1 → XP_054174966.1  metallophosphoesterase 1 isoform X1

  11. XM_054319013.1 → XP_054174988.1  metallophosphoesterase 1 isoform X6

  12. XM_054319003.1 → XP_054174978.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93

  13. XM_054318996.1 → XP_054174971.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4

  14. XM_054318988.1 → XP_054174963.1  metallophosphoesterase 1 isoform X1

  15. XM_054318998.1 → XP_054174973.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4

  16. XM_054318995.1 → XP_054174970.1  metallophosphoesterase 1 isoform X1

  17. XM_054319014.1 → XP_054174989.1  metallophosphoesterase 1 isoform X6

  18. XM_054319000.1 → XP_054174975.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4

  19. XM_054318990.1 → XP_054174965.1  metallophosphoesterase 1 isoform X1

  20. XM_054318994.1 → XP_054174969.1  metallophosphoesterase 1 isoform X1

  21. XM_054319005.1 → XP_054174980.1  metallophosphoesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A0A0MR93

  22. XM_054318999.1 → XP_054174974.1  metallophosphoesterase 1 isoform X2

    UniProtKB/Swiss-Prot
    B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q53F39, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4

  23. XM_054318993.1 → XP_054174968.1  metallophosphoesterase 1 isoform X1

  24. XM_054319012.1 → XP_054174987.1  metallophosphoesterase 1 isoform X5

  25. XM_054319009.1 → XP_054174984.1  metallophosphoesterase 1 isoform X5

  26. XM_054319008.1 → XP_054174983.1  metallophosphoesterase 1 isoform X4

  27. XM_054319011.1 → XP_054174986.1  metallophosphoesterase 1 isoform X5

  28. XM_054319018.1 → XP_054174993.1  metallophosphoesterase 1 isoform X10

  29. XM_054319015.1 → XP_054174990.1  metallophosphoesterase 1 isoform X7

  30. XM_054319010.1 → XP_054174985.1  metallophosphoesterase 1 isoform X5

  31. XM_054319017.1 → XP_054174992.1  metallophosphoesterase 1 isoform X9

  32. XM_054319016.1 → XP_054174991.1  metallophosphoesterase 1 isoform X8

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_138608.2: Suppressed sequence

    Description
    NM_138608.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q53F39.2 GenPept UniProtKB/Swiss-Prot:Q53F39

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